THE EFFECTS OF DEPRESSION AND AGE ON THE HORNE-OSTBERG MORNINGNESS EVENINGNESS SCORE
THE EFFECTS OF DEPRESSION AND AGE ON THE HORNE-OSTBERG MORNINGNESS EVENINGNESS SCORE
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DOI：
10.1016/0165-0327(91)90096-b
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发表时间：
1991-10-01
影响因子：
6.6
通讯作者：
GOYETTE, LM
中科院分区：
文献类型：
--
作者：
DRENNAN, MD;KLAUBER, MR;GOYETTE, LM
本研究评估了抑郁症和年龄对志愿者Horne-Ostberg晨夜量表的影响。39名目前患有DSM-IIIR抑郁症的健康门诊患者，没有最近的药物滥用或混合药物，与39名年龄和性别匹配的对照组进行了比较。患者报告比对照组有更多的“夜晚”(P=0.014，威尔科森符号列检验)。抑郁组的Horne-Ostberg量表得分分布呈多态分布，而对照组呈正态分布。年龄与Horne-Ostberg评分呈正相关(r=0.42~0.55)。抑郁和年龄影响Horne-Ostberg评分。抑郁症患者昼夜节律的多态现象值得进一步研究。
Effects of depression and age on the Horne-Ostberg morningness-eveningness scale in human volunteers were assessed. Thirty-nine healthy outpatients with current DSM-IIIR depression, free of recent substance abuse or confounding medications, were compared to 39 age- and sex-matched controls. Patients reported greater 'eveningness' than controls (P = 0.014, Wilcoxon signed-ranks test). There was multimodality in the distribution of Horne-Ostberg scale scores in the depressed group, but a normal distribution in controls. Pearson's correlation of age vs. Horne-Ostberg score was positive (r = 0.42-0.55). Depression and age influence the Horne-Ostberg score. Potential multimodality of circadian phase in the depressed group deserves further study.