DEMOGRAPHIC STUDY OF DISEASE DUE TO MYCOBACTERIUM-KANSASII OR M-INTRACELLULARE-AVIUM IN TEXAS
DEMOGRAPHIC STUDY OF DISEASE DUE TO MYCOBACTERIUM-KANSASII OR M-INTRACELLULARE-AVIUM IN TEXAS
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DOI：
10.1378/chest.75.2.120
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发表时间：
1979-01-01
期刊：
影响因子：
9.6
通讯作者：
HURST, GA
中科院分区：
文献类型：
--
作者：
AHN, CH;LOWELL, JR;HURST, GA
从1967年1月到1976年12月，在美国德克萨斯州，据报道由堪萨斯分枝杆菌或鸟胞内分枝杆菌引起的疾病的患者数量有所增加，而肺结核则有所减少。本文分析了1409例感染堪萨斯分枝杆菌和706例感染细胞内鸟状分枝杆菌的病例。前者聚集在城市地区，发病率是非城市地区的两倍多（P < 0.001）。后者分布更为分散，非城市地区的发病率约为城市地区的两倍（P < 0.001）。感染堪萨斯分枝杆菌组的平均年龄为50岁，感染细胞内鸟分枝杆菌组的平均年龄为58岁。在仅感染堪萨斯分枝杆菌的患者中，男性的平均年龄明显高于女性。两组间均存在雄性优势，即甘肃分枝杆菌为3:1，胞内分枝杆菌为2:1。具有西班牙姓氏的人因堪萨斯分枝杆菌感染的发病率较低。没有注意到其他种族或族裔的联系。讨论了确定非典型分枝杆菌病所涉及的各种因素。
The number of patients reported to have disease due to M. kansasii or M. intracellulare-avium increased in Texas [USA] from Jan. 1967 to Dec. 1976, in contrast to a decrease in tuberculosis. Presented is an analysis of 1409 patients infected with M. kansasii and 706 patients infected with M. intracellular-avium. The former group clustered in urban areas with more than twice the incidence compared to nonurban areas (P < 0.001). The latter group was more diffusely distributed with approximately twice the incidence in nonurban areas compared to urban areas (P < 0.001). The average age of the group infected with M. kansasii was 50 yr and of the group infected with M. intracellular-avium 58 yr. In patients infected with M. kansasii only, the average age was significantly higher for men than women. There was a male predominance in both groups, i.e., 3:1 in M. kansasii and 2:1 in M. intracellulare-avium. Persons with Spanish surnames had a low incidence of disease due to M. kansasii. No other racial or ethnic association was noted. The various factors involved in determining the atypical mycobacterial diseases are discussed.