Quantification of regional calcium burden in chronic total occlusion by 64-slice multi-detector computed tomography and procedural outcomes of percutaneous coronary intervention
Quantification of regional calcium burden in chronic total occlusion by 64-slice multi-detector computed tomography and procedural outcomes of percutaneous coronary intervention
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DOI：
10.1016/j.ijcard.2009.05.006
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发表时间：
2010-11-05
影响因子：
3.5
通讯作者：
Jang, Yangsoo
中科院分区：
文献类型：
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作者：
Cho, Jung Rae;Kim, Young Jin;Jang, Yangsoo
背景：慢性完全闭塞（CTO）经皮冠状动脉介入治疗（PCI）失败的最重要原因之一是钙化斑块，它要么阻止导丝通过，要么在球囊膨胀后破裂。我们试图评估多排计算机断层扫描 (MDCT) 上量化的 CTO 钙含量是否与即时手术结果相关。方法：对 64 名患有 72 个 CTO 病变且在 PCI 之前接受 64 层 MDCT 的患者进行了调查。根据手术结果将病灶分为2组（PCI成功组55个病灶，PCI失败组17个病灶）。比较两组的临床、血管造影和MDCT参数，包括局部钙体积（RCaV）、局部钙评分（RCaS）、局部钙当量质量（RCaEq）和CTO最钙化横截面的相对钙面积（%CaS/CSA）。结果：PCI成功组的CTO持续时间短于PCI失败组（7.16+/-10.5 vs 15.59+/-） 14.92 个月，p = 0.011），手术成功率为 76.3%。区域钙相关参数（RCaV 52.86 +/- 58.39 vs 7.26 +/- 15.27 mm(3)，p
Background: One of the most important reasons for failure of percutaneous coronary intervention (PCI) in chronic total occlusion (CTO) is calcified plaque, which either prevents passage of guide wire or ruptures after balloon inflation. We sought to evaluate whether quantified calcium contents of CTO on multi-detector computed tomography (MDCT) correlate with immediate procedural outcomes.Methods: Sixty-four patients with 72 CTO lesions who underwent 64-slice MDCT prior to PCI were investigated. The lesions were divided into 2 groups according to procedural outcomes (55 lesions with PCI-success group, 17 lesions with PCI-failure group). Clinical, angiographic and MDCT parameters, including regional calcium volume (RCaV), regional calcium score (RCaS), regional calcium equivalent mass (RCaEq), and relative calcium area at the most calcified cross section of CTO (%CaS/CSA), were compared between the two groups.Results: The duration of CTO was shorter in PCI-success group than PCI-failure group (7.16 +/- 10.5 vs 15.59 +/- 14.92 months, p = 0.011), and the procedural success rate was 76.3%. Regional calcium-related parameters (RCaV 52.86 +/- 58.39 vs 7.26 +/- 15.27 mm(3), p