Nonlinear frequency response functions of a chromatographic column—A critical evaluation of their potential for estimation of single solute adsorption isotherms
Nonlinear frequency response functions of a chromatographic column—A critical evaluation of their potential for estimation of single solute adsorption isotherms
复制标题
色谱柱的非线性频率响应函数——对其估计单一溶质吸附等温线潜力的关键评估
DOI：
10.1016/j.ces.2006.11.019
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发表时间：
2007
影响因子：
4.7
通讯作者：
A. Seidel
中科院分区：
文献类型：
--
作者：
M. Ilic;M. Petkovska;A. Seidel
采用非线性频响分析方法研究了色谱柱中单组分的吸附行为。根据色谱柱高阶频率响应函数的低频渐近行为，可以从指定稳态浓度下的吸附等温线的局部导数估算出单组分的吸附等温线。与吸附等温线估算相关的函数是这些FRF的相和一阶导数。对不同类型的吸附等温线模型、不同的等温线参数、稳态浓度和色谱柱的理论板数进行了分析。在此分析的基础上，观察到了这些函数的一些统一的特征，这些特征可用于对该方法的批判性评价和为其应用设计有效的实验程序。讨论了该方法的优点和局限性。
Nonlinear frequency response analysis is applied to study single component adsorption in chromatographic columns. Single component adsorption isotherms can be estimated from local derivatives of the adsorption isotherm at specified steady-state concentrations, which are obtained from the low frequency asymptotic behavior of the higher order frequency response functions (FRFs) of a chromatographic column. The functions relevant for the estimation of adsorption isotherms are the phases and the first derivatives of these FRFs. These functions (up to the third order) are analyzed for different types of adsorption isotherm models, different isotherm parameters, steady-state concentrations and numbers of theoretical plates of the chromatographic column. Based on this analysis, some unified characteristics of these functions are observed, which can be used for critical evaluation of the method and to design efficient experimental procedures for its application. Advantages and limitations of this method are discussed.