Mild renal failure is associated with adverse outcome after cardiac valve surgery
Mild renal failure is associated with adverse outcome after cardiac valve surgery
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DOI：
10.1016/s0272-6386(00)70050-3
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发表时间：
2000-06-01
影响因子：
13.2
通讯作者：
Shroyer, L
中科院分区：
文献类型：
--
作者：
Anderson, RJ;O'Brien, M;Shroyer, L
本研究旨在确定轻度肾功能衰竭（定义为血清肌酐浓度为1.5 - 3.0 mg/dL）是否是一个独立的危险因素。心脏瓣膜手术后的不良反应。我们收集了14个退伍军人事务医疗中心834名接受心脏瓣膜手术的患者的广泛的术前和术后数据。进行单变量和多变量分析以确定是否存在轻度肾功能不全与不良结局的独立关联。轻度肾功能衰竭患者的每日死亡率（P = 0.001； 16%对6%）、术后出血频率（P = 0.023； 16%对8%）、呼吸系统并发症（P = 0.02, 29%对16%）和心脏并发症（P = 0.002； 18%对7%）明显高于肾功能正常患者(血清肌酐
The present study was performed to ascertain whether the presence of mild renal failure (defined as a serum creatinine concentration of 1.5 to 3.0 mg/dL) is an independent risk factor. for adverse outcome after cardiac valve surgery. An extensive set of preoperative and postoperative data was collected in 834 prospectively evaluated patients undergoing cardiac valve surgery at 14 Veterans Affairs Medical Centers. Univariate and multivariable analyses were performed to determine whether an independent association of mild renal dysfunction with adverse outcomes was present. Patients with mild renal failure had significantly greater do-day mortality rates (P = 0.001; 16% versus 6%) and frequency of postoperative bleeding (P = 0.023; 16% versus 8%), respiratory complications (P = 0.02, 29% versus 16%), and cardiac complications (P = 0.002; 18% versus 7%) than patients with normal renal function (serum creatinine