Plasmodium falciparum:: Enhanced gametocyte formation in vitro in reticulocyte-rich blood
Plasmodium falciparum:: Enhanced gametocyte formation in vitro in reticulocyte-rich blood
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DOI：
10.1006/expr.1998.4347
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发表时间：
1999-02-01
影响因子：
2.1
通讯作者：
Nagle, RL
中科院分区：
文献类型：
--
作者：
Trager, W;Gill, GS;Nagle, RL
将配子体形成克隆HB-3的晚期寄生虫浓缩物与贫血患者富含网织红细胞的血液或正常对照血液混合，在培养条件下保存4天。富含网织红细胞的血液中形成的配子体明显多于对照组。无论贫血的血液支持的无性寄生虫血症比对照组大，还是比对照组低，还是相同，并且不考虑贫血的原因，这都是正确的。在富含网织红细胞的血液中，配子体占无性形式的百分比比正常血液高出10倍。(C)1999年学术出版社。
Concentrates of late stage parasites of the gametocyte-forming clone HB-3 were mixed with blood rich in reticulocytes from anemic patients, or with normal control blood, and kept under culture conditions for 4 days. Significantly more gametocytes were always formed in the reticulocyte-rich blood than in the control. This was true whether the anemic blood supported a larger asexual parasitemia than the control, or a lower one, or the same and without regard to the cause of the anemia. Gametocytes as a percentage of asexual forms were up to 10 times higher in reticulocyte-rich blood than in normal blood. (C) 1999 Academic Press.