Association of Serum Uric Acid With Aortic Stiffness and Pressure in a Chinese Workplace Setting
Association of Serum Uric Acid With Aortic Stiffness and Pressure in a Chinese Workplace Setting
复制标题
中国工作场所血清尿酸与主动脉僵硬度和压力的关系
DOI：
10.1038/ajh.2009.277
复制
发表时间：
2010-04-01
影响因子：
3.2
通讯作者：
Wang, Ji-Guang
中科院分区：
文献类型：
--
作者：
Chen, Xin;Li, Yan;Wang, Ji-Guang
在本分析中，我们调查了血尿酸与主动脉僵硬度和压力的关系，测量颈动脉-股动脉脉搏波速度（cf-PWV）和中心收缩压（SBP），分别METHODS我们的研究是在一个工厂的员工及其家庭成员（年龄15-79岁）的心血管健康检查的框架。我们使用SphygmoCor器械进行动脉测量。高尿酸血症定义为男性血清尿酸浓度至少为420 μ mol/l，女性至少为360 μ mol/l。940名研究参与者包括207名（22.0%）高血压患者，其中92名（9.8%）服用抗高血压药物。男性（n = 620）与女性（n = 320）相比，
BACKGROUNDIn the present analysis, we investigated the association of serum uric acid with aortic stiffness and pressure as measured by carotid-femoral pulse wave velocity (cf-PWV) and central systolic blood pressure (SBP), respectively.METHODSOur study was conducted in the framework of cardiovascular health examinations for the employees of a factory and their family members (ages 15-79 years). We performed arterial measurements using the SphygmoCor device. Hyperuricemia was defined as a serum uric acid concentration of at least 420 mu mol/l in men and 360 mu mol/l in women.RESULTSThe 940 study participants included 207(22.0%) hypertensive patients, of whom 92(9.8%) took antihypertensive medication. Men (n = 620), compared with women (n = 320), had significantly (P