HOTAIR upregulates an 18-gene cell cycle-related mRNA network in glioma
HOTAIR upregulates an 18-gene cell cycle-related mRNA network in glioma
复制标题
HOTAIR 上调神经胶质瘤中 18 个基因细胞周期相关 mRNA 网络
DOI：
10.3892/ijo.2017.3901
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发表时间：
2017-04-01
影响因子：
5.2
通讯作者：
Wang, Qixue
中科院分区：
文献类型：
--
作者：
Huang, Kai;Sun, Jia;Wang, Qixue
HOTAIR是一种促进肿瘤生长的长非编码RNA(IncRNA)，在多种癌症中发挥作用。然而，HOTAIR在胶质瘤中的作用还没有得到很好的研究。从中国人脑胶质瘤基因组图谱中鉴定出与HOTAIR正相关的基因，并构建成一个相互作用的网络。总共有18个基因具有P值
HOTAIR is a tumor promoting long non-coding RNA (IncRNA) with roles in multiple cancers. However, the role of HOTAIR in glioma has not been well charaterized. Genes that positively correlated with HOTAIR were identified from the Chinese Glioma Genome Atlas and constructed into an interacting network. In total, 18 genes with P-values