The safety and tolerability of inhaled treprostinil in patients with pulmonary hypertension and chronic obstructive pulmonary disease
The safety and tolerability of inhaled treprostinil in patients with pulmonary hypertension and chronic obstructive pulmonary disease
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DOI：
10.1086/689291
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发表时间：
2017-01-01
影响因子：
2.6
通讯作者：
Burger, Charles D.
中科院分区：
文献类型：
--
作者：
Bajwa, Abubakr A.;Shujaat, Adil;Burger, Charles D.
主要目的是探索吸入曲前列尼尔用于肺动脉高压（PH）伴慢性阻塞性肺疾病（COPD）患者的安全性和耐受性。诊断为毛细血管前PH的患者（定义为肺动脉平均压>= 25 mmHg，肺动脉楔压或左心室舒张末期压> 25 mmHg）
The primary aim was to explore the safety and tolerability of inhaled treprostinil when used in patients with pulmonary hypertension (PH) with concomitant chronic obstructive pulmonary disease (COPD). Patients with a diagnosis of pre-capillary PH (defined as pulmonary artery mean pressure of >= 25 mmHg and pulmonary artery wedge pressure or left ventricular end diastolic pressure of