Inhibitory changes after age 60 and their relationship to measures of attention and memory

Inhibitory changes after age 60 and their relationship to measures of attention and memory
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DOI:
10.1093/geronb/57.3.p223
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发表时间:
2002-05-01
影响因子:
6.2
通讯作者:
Denburg, NL
Denburg, NL
中科院分区:
医学1区
文献类型:
--
作者:
Persad, CC;Abeles, N;Denburg, NL

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本研究探讨了年龄和抑制功能之间的关系,年龄范围从60岁到85岁的老年人的样本。在早期研究的基础上,并通过因素分析证实,通常被称为额叶任务的措施被用作抑制功能的措施。研究结果表明,抑制过程继续下降,随着年龄的增长,在老年人的样本。此外,抑制在年龄相关的性能缺陷的口头列表学习措施和注意力措施的作用进行了检查。分层回归分析表明,抑制占一个显着的比例与年龄相关的方差的两个认知措施,而措施的阅读速度占一个较小的比例的方差。此外,当抑制第一次协变,阅读速度不再占显着比例的年龄相关的方差。有人认为,抑制是一个重要的贡献者与年龄相关的性能递减的认知。
This study examined the relationship between age and inhibitory functioning within a sample of older adults ranging in age from 60 to 85 years old. On the basis of earlier research, and confirmed by factor analysis, measures typically referred to as frontal lobe tasks were used as measures of inhibitory functioning. Findings demonstrated that inhibitory processes continued to decline with advancing age within the older sample. In addition, the role of inhibition in age-related performance deficits on a verbal list learning measure and an attention measure was examined. Hierarchical regression analyses showed that inhibition accounted for a significant proportion of the age-related variance on the two cognitive measures, whereas measures of reading speed accounted for a smaller proportion of the variance. In addition, when inhibition was first covaried out, reading speed no longer accounted for a significant proportion of the age-related variance. It is argued that inhibition is an important contributor to age-related performance decrements in cognition.