Remote Administration of Physical and Cognitive Performance Assessments in a Predominantly Black Cohort of Persons With Systemic Lupus Erythematosus.

Remote Administration of Physical and Cognitive Performance Assessments in a Predominantly Black Cohort of Persons With Systemic Lupus Erythematosus.
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DOI:
10.1002/acr2.11588
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发表时间:
2023-09
影响因子:
3.4
通讯作者:
--
中科院分区:
其他
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在一项针对主要患有系统性红斑狼疮 (SLE) 的黑人患者的身体和认知功能的研究中,我们将远程管理的身体和认知表现评估与亲自收集的评估进行了比较。我们招募了 2021 年至 2022 年在家长研究中完成面对面访问的一部分参与者 (n = 30),以在 28 天内完成第二次远程访问。两次访视均测量了身体表现(通过改良的短期身体表现电池 [SPPB] 测量;范围 0-12;子量表范围 0-4;较高 = 更好的表现)和认知表现(情景和工作记忆调整 t 分数,使用 NIH Toolbox 测量)。使用配对 t 检验比较平均分数;组内相关系数(ICC)是从双向混合效应模型中获得的。使用线性和逻辑模型来估计绩效指标和相关结果之间的分层关联。参与者主要是女性(93.3%)和黑人(93.3%)。与远程相比,现场总体 SPPB(8.76 比 9.43)和椅子站立(1.43 比 1.90)得分在统计上显着较低。与远程访问相比,面对面访问的情景记忆(47.27 vs. 49.53)和工作记忆(45.37 vs. 47.90)的 t 分数较低。整体 SPPB 的 ICC 表现出良好的一致性 (0.76),而情景 (0.49) 和工作记忆 (0.57) 的 ICC 表现出较差至中等的一致性。绩效评估与相关结果之间的关联相似,并且根据访视方式没有统计学上的显着差异。为了尽可能扩大 SLE 身体和认知表现研究的参与者群体并使其多样化,未来的研究应考虑远程管理评估。
In a study of physical and cognitive functioning among predominantly Black individuals with systemic lupus erythematosus (SLE), we compared remotely administered physical and cognitive performance assessments to those collected in person. A subset of participants who completed an in‐person visit in our parent study from 2021 to 2022 (n = 30) were recruited to complete a second, remote visit within 28 days. Physical performance (measured by a modified Short Physical Performance Battery [SPPB]; range 0‐12; subscale ranges 0‐4; higher = better performance) and cognitive performance (episodic and working memory adjusted t‐scores, measured using NIH Toolbox) were measured at both visits. Mean scores were compared using paired t‐tests; intraclass correlation coefficients (ICCs) were obtained from two‐way mixed effects models. Linear and logistic models were used to estimate stratified associations between performance measures and related outcomes. Participants were primarily female (93.3%) and Black (93.3%). In‐person versus remote overall SPPB (8.76 vs. 9.43) and chair stand (1.43 vs. 1.90) scores were statistically significantly lower. t‐Scores for episodic memory (47.27 vs. 49.53) and working memory (45.37 vs. 47.90) were lower for in‐person versus remote visits. The ICC for overall SPPB indicated good agreement (0.76), whereas the ICCs for episodic (0.49) and working memory (0.57) indicated poor‐moderate agreement. Associations between assessments of performance with related outcomes were similar and did not statistically significantly differ by modality of visit. To possibly expand and diversify pools of participants in studies of physical and cognitive performance in SLE, remote administration of assessments should be considered for future research.
DOI: 10.1002/acr2.11370
发表时间: 2022-03
影响因子: 3.4
作者:
Bell K;Dykas C;Muckian B;Williams B;Rainey H;Comberg M;Mora M;Owen KA;Lipsky PE
通讯作者: Lipsky PE