Endodontic treatment of primary teeth using a combination of antibacterial drugs
Endodontic treatment of primary teeth using a combination of antibacterial drugs
复制标题
DOI：
10.1111/j.0143-2885.2004.00771.x
复制
发表时间：
2004-02-01
影响因子：
5
通讯作者：
Hoshino, E
中科院分区：
文献类型：
--
作者：
Takushige, T;Cruz, EV;Hoshino, E
目的评价“病灶灭菌与组织修复”（病灶灭菌与组织修复）治疗乳牙根管治疗的临床效果。方法采用甲硝唑、环丙沙星、米诺环素（3Mix）混合药膏（大醇混合丙二醇：MP）或根管密封器对56例4 ~ 18岁感染的患者进行根管消毒。在87例乳牙中，81例发生生理性牙根吸收。根周共出现54个透光病灶。消毒前后未准备根管。将3Mix药物（3Mix- mp /3Mix-sealer）放置在根管孔或牙髓腔底部，用玻璃离子水门栓密封，再用直接法制备的复合树脂嵌体加固，并用树脂胶结。结果所有病例的牙龈肿胀（52例）、窦道肿大（22例）、诱发性钝痛（3例）、自发性钝痛（26例）、咬痛（46例）等临床症状均经治疗后消失，其中4例患者经相同治疗后，临床症状和体征才得到缓解。因此，牙龈脓肿和瘘管，如果存在，在几天后消失。继发恒牙萌出无异常，或在萌出过程中x线片显示正常。所有病例均被评价为成功。除1例继位恒牙先天缺失外，乳牙平均功能时间为680天（范围：68-2390天）。结论LSTR牙髓治疗根周病变伴或不伴生理性根吸收的乳牙均能成功治疗。
Aim To evaluate the clinical outcome of 'Lesion Sterilization and Tissue Repair' (LSTR) therapy for endodontic treatment of primary teeth.Methodology A mixture of metronidazole, ciprofloxacin, and minocycline (3Mix) in ointment (macrogol mixed with propylene glycol: MP) or in a root canal sealer was used to disinfect infected root canals of 56 patients aged 4-18 years. Out of a total of 87 primary teeth, 81 cases had physiologic root resorption. A total of 54 radiolucent periradicular lesions were present. The root canals were not prepared before or after disinfection. 3Mix medicament (3Mix-MP/3Mix-sealer) was placed at orifices of root canals or on the bottom of pulp chambers, and then sealed with glass-ionomer cement and further reinforced by a composite resin inlay prepared using a direct method and cemented with resin.Results In all cases, clinical symptoms such as gingival swelling (52 cases), sinus tracts (22 cases), induced dull pain (3 cases), spontaneous dull pain (26 cases), and pain on biting (46 cases) disappeared after treatment, although in four cases clinical signs and symptoms were finally resolved only after retreatment using the same procedures. Thus, gingival abscesses and fistulae, if present, disappeared after a few days. Successor permanent teeth erupted without any disorders, or were found radiographically to be normal and in the process of eruption. All the cases were evaluated as successful. The mean function time of the primary teeth was 680 days (range: 68-2390 days), except for one case in which the successor permanent tooth was congenitally missing.Conclusion Primary teeth with periradicular lesions with or without physiologic root resorption were treated successfully by the LSTR endodontic therapy.