Recurrent endocrine mucin-producing sweat gland carcinoma in the eyelid.
Recurrent endocrine mucin-producing sweat gland carcinoma in the eyelid.
复制标题
眼睑复发性内分泌粘蛋白汗腺癌。
DOI：
10.1111/j.1440-0960.2011.00857.x
复制
发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Yamanaka S.
中科院分区：
文献类型：
--
作者：
Koike T;Mikami T;Maegawa J;Iwai T;Wada H;Yamanaka S.
产生内分泌粘蛋白的汗腺癌（EMPSGC）最近被认为是一种几乎总是发生在眼睑上的低度恶性肿瘤。这种癌是非常罕见的，只有20例（包括本例）已在文献中报道。EMPSGC常与浸润性粘液癌相关。虽然EMPSGC治疗包括完全手术切除，但关于手术切缘尚未达成共识。因此，EMPSGC的外科治疗报告可能提供重要的治疗信息。在这里，我们介绍了一例74岁男性眼睑EMPSGC，尽管在另一家机构进行了手术治疗，但反复复发。转诊至我科后，患者接受了肿瘤切除术。然而，标本显示手术切缘阳性，因此，他随后接受了更广泛的切除。在他最后一次手术后6个月，没有肿瘤复发或转移的迹象。本文回顾了目前的文献，并讨论了EMPSGC的手术治疗。
Endocrine mucin‐producing sweat gland carcinoma (EMPSGC) has recently been recognised as a low‐grade carcinoma that almost always occurs on the eyelid. This carcinoma is very rare, with only 20 cases (including the present one) having been reported in the literature. EMPSGC is frequently found in association with invasive mucinous carcinoma. While EMPSGC treatments consist of a complete surgical removal, there has been no consensus regarding the surgical margin. Therefore, reports on surgical management of EMPSGC may potentially provide important therapeutic information. Here, we present a case of a 74‐year‐old man with EMPSGC of the eyelid that repeatedly recurred despite surgical treatments at another institution. After referral to our department, the patient underwent tumour excision. However, the specimen revealed a positive surgical margin and thus, he subsequently underwent a wider excision. There has been no sign of tumour recurrence or metastasis 6 months after his last operation. This article reviews the current literature and discusses the surgical management of EMPSGC.