Use of national pneumonia surveillance to describe influenza A(H7N9) virus epidemiology, China, 2004-2013.

Use of national pneumonia surveillance to describe influenza A(H7N9) virus epidemiology, China, 2004-2013.
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DOI:
10.3201/eid1911.130865
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发表时间:
2013-11
影响因子:
11.8
通讯作者:
Feng Z
Feng Z
中科院分区:
医学2区
文献类型:
--
作者:
Xiang N;Havers F;Chen T;Song Y;Tu W;Li L;Cao Y;Liu B;Zhou L;Meng L;Hong Z;Wang R;Niu Y;Yao J;Liao K;Jin L;Zhang Y;Li Q;Widdowson MA;Feng Z

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在中国大陆,2013年春季大部分甲型H7N9禽流感病例是通过不明原因肺炎(PUE)监测系统报告的。为了了解可能的漏报和监测偏差在评估 H7N9 亚型病例流行病学以及活禽市场关闭的影响方面的作用,我们检查了 2004 年至 2013 年 5 月 3 日报告的所有 PUE 病例。历史上,PUE 系统未得到充分利用,报告不一致,PUE 报告偏向于受 A(H7N9) 影响的省份,未受影响省份的数据稀疏;然而,我们没有发现任何证据表明 A(H7N9) 感染者的年龄较大是由监测偏差造成的。活禽市场关闭后,确诊为甲型H7N9的PUE病例的绝对数量和比例有所下降(p<0.001),表明市场关闭可能对疫情控制产生了积极影响。在中国,PUE监测需要改进。
In mainland China, most avian influenza A(H7N9) cases in the spring of 2013 were reported through the pneumonia of unknown etiology (PUE) surveillance system. To understand the role of possible underreporting and surveillance bias in assessing the epidemiology of subtype H7N9 cases and the effect of live-poultry market closures, we examined all PUE cases reported from 2004 through May 3, 2013. Historically, the PUE system was underused, reporting was inconsistent, and PUE reporting was biased toward A(H7N9)-affected provinces, with sparse data from unaffected provinces; however, we found no evidence that the older ages of persons with A(H7N9) resulted from surveillance bias. The absolute number and the proportion of PUE cases confirmed to be A(H7N9) declined after live-poultry market closures (p<0.001), indicating that market closures might have positively affected outbreak control. In China, PUE surveillance needs to be improved.
人类感染新型禽源甲型流感 (H7N9) 病毒。
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发表时间: 2013-05-16
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