Single Nucleotide Polymorphism in the LDHA Gene as a Potential Marker for the Racing Performance of Pigeons
Single Nucleotide Polymorphism in the LDHA Gene as a Potential Marker for the Racing Performance of Pigeons
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DOI：
10.2141/jpsa.0130237
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发表时间：
2014-10-01
影响因子：
1.5
通讯作者：
Dybus, Andrzej
中科院分区：
文献类型：
--
作者：
Proskura, Witold S.;Cichon, Daria;Dybus, Andrzej
本研究旨在探讨编码乳酸脱氢酶A亚型的乳酸脱氢酶A基因(LDHA)中的g.2582481G>；A、g.2583935G>；A和g.2584057C>；T单核苷酸多态(SNPs)与信鸽赛跑性能的关系。作为衡量比赛表现的指标，我们使用了整个赛季中单个鸟类获得的王牌积分的平均值。鸽子比赛成绩的估计遗传力较低(h(2)=0)。0596；SE=0.0249)。对所有比赛报告进行的分析表明，性别、比赛开始和结束时的天气条件等因素影响所分析的特征。在3个单核苷酸多态中，只有g.2582481G>；A基因对赛鸽生产性能有显著影响。统计分析表明，GG和GA两种基因在G2582481G和GT；A SNP的ACE值上存在差异。研究表明，g.2582481a纯合子的基因型与ACE点的最高平均值相关联。从而揭示了g.2582481G和gt；A基因与赛车成绩的关系。
The objective of the present study was to investigate the relationship between the g.2582481G>A, g.2583935G>A and g.2584057C>T single nucleotide polymorphisms (SNPs) within the lactate dehydrogenase A gene (LDHA) coding for lactate dehydrogenase isoform A and the racing performance of homing pigeons. As a measure of racing performance, we used the mean values of ace points won by individual birds during the whole season. The estimated heritability of the racing performance of pigeons was relatively low (h(2)=0. 0596; SE=0.0249). The analysis performed for all race reports together showed that the factors such as gender, weather conditions at the start and at the end of the race affect the analyzed trait. Of the 3 single nucleotide polymorphisms, only the effect of the g.2582481G>A genotype on the performance of racing pigeons was significant. Statistical analysis indicated the difference in the value of ace points between the animals of GG and GA genotypes for the g.2582481G>A SNP. The study showed that the genotype homozygous for g.2582481A is linked to the highest mean value of ace points. Consequently, the relationship between the genotype for g.2582481G>A and the racing performance was shown.