High-protein intake enhances the positive impact of physical activity on BMC in prepubertal boys
High-protein intake enhances the positive impact of physical activity on BMC in prepubertal boys
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DOI：
10.1359/jbmr.070907
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发表时间：
2008-01-01
影响因子：
6.2
通讯作者：
Rizzoli, Rene
中科院分区：
文献类型：
--
作者：
Chevalley, Thierry;Bonjour, Jean-Philippe;Rizzoli, Rene
在232个健康的青春期前的男孩，增加体力活动与更大的BMC在轴向和appericular网站下的高蛋白Introduction：体力活动是一个重要的生活方式的决定因素，骨矿物质的收购。它对儿童的影响可以通过营养，特别是蛋白质和钙的摄入来调节。我们分析了身体活动水平和蛋白质与钙摄入量之间的关系，对BMC.Materials和方法：在232个健康的青春期前男孩（年龄：7.4 +/- 0.4 [SD] yr;身高：125.7 +/- 5.9 cm;体重：25.3 +/- 4.6 kg），身体活动和蛋白质和钙的摄入量进行了记录。结果：在单因素分析中，各骨骼部位的BMC与体力活动的相关系数r为0.26 ~ 0.99，与年龄、性别、年龄、性别、（p = 0.0001）至0.40（p = 0.0001）;蛋白质摄入量从0.18（p = 0.005）至0.27（p = 0.0001）;钙摄入量从0.09（p = 0.181）至0.17（p = 0.007）。通过多元回归分析，P调整值与BMC保持相关性，范围如下：体力活动，从0.219（p = 0.0007）到0.340（p < 0.0001）;蛋白质摄入量，从0.120（p = 0.146）到0.217（p = 0.009）。相比之下，它与钙摄入量无关：从-0.069（p = 0.410）到0.001（p = 0.986）。蛋白质摄入量（平均值= 2.0 g/kg体重/d）高于中位数时，体力活动从168 kcal/d增加至321 kcal/d与平均BMC Z评分增加相关（+0.6，p = 0.0005）。与低于中位数的蛋白质摄入量（平均值= 1.5 g/kg体重/d）相比，体力活动从167 kcal/d增加到312 kcal/d与平均BMC Z评分显著增加无关（+0.2，p = 0.371）。体力活动和蛋白质摄入量之间的相互作用对于平均BMC Z评分接近统计学显著性（p = 0.055），对于股骨颈BMC显著性（p = 0.012）。在符合来自多元回归分析的结果，增加体力活动的平均BMC Z-评分不受钙摄入量的差异以上（平均值= 945毫克/天）和以下（平均值= 555毫克/天）medium.Conclusion：在健康的青春期前男孩，增加体力活动对BMC的影响似乎是增强蛋白质摄入量的限制在通常的建议津贴。
In 232 healthy prepubertal boys, increased physical activity was associated with greater BMC at both axial and appendicular sites under high-protein intake.Introduction: Physical activity is an important lifestyle determinant of bone mineral mass acquisition. Its impact during childhood can be modulated by nutrition, particularly by protein and calcium intakes. We analyzed the relationship between physical activity levels and protein compared with calcium intake on BMC.Materials and Methods: In 232 healthy prepubertal boys (age: 7.4 +/- 0.4 [SD] yr; standing height: 125.7 +/- 5.9 cm; body weight: 25.3 +/- 4.6 kg), physical activity and protein and calcium intakes were recorded. BMC was measured by DXA at the radial metaphysis, radial diaphysis, total radius, femoral neck, total hip, femoral diaphysis, and L-2-L-4 vertebrae.Results: In univariate analysis, the correlation coefficients r with BMC of the various skeletal sites were as follows: physical activity, from 0.26 (p = 0.0001) to 0.40 (p = 0.0001); protein intake, from 0.18 (p = 0.005) to 0.27 (p = 0.0001); calcium intake, from 0.09 (p = 0.181) to 0.17 (p = 0.007). By multiple regression analysis, the P-adjusted values remained correlated with BMC, ranging as follows: physical activity, from 0.219 (p = 0.0007) to 0.340 (p < 0.0001); protein intake, from 0.120 (p = 0.146) to 0.217 (p = 0.009). In contrast, it was not correlated for calcium intake: from -0.069 (p = 0.410) to 0.001 (p = 0.986). With protein intake (mean = 2.0 g/kg body weight/d) above the median, increased physical activity from 168 to 321 kcal/d was associated with greater mean BMC Z-score (+0.6, p = 0.0005). In contrast with protein intake (mean = 1.5 g/kg body weight/d) below the median, increased physical activity from 167 to 312 kcal/d was not associated with a significantly greater mean BMC Z-score (+0.2, p = 0.371). The interaction between physical activity and protein intake was close to statistical significance for mean BMC Z-score (p = 0.055) and significant for femoral neck BMC (p = 0.012). In keeping with the results derived from multiple regression analysis, the increased physical activity on mean BMC Z-score was not influenced by difference in calcium intake above (mean = 945 mg/d) and below (mean = 555 mg/d) the median.Conclusion: In healthy prepubertal boys, the impact in increased physical activity on BMC seems to be enhanced by protein intake within limits above the usual recommended allowance.