Improved first-pass spiral myocardial perfusion imaging with variable density trajectories.
Improved first-pass spiral myocardial perfusion imaging with variable density trajectories.
复制标题
DOI:
10.1002/mrm.24569
复制
发表时间:
2013-11
影响因子:
3.3
通讯作者:
Meyer, Craig H.
中科院分区:
文献类型:
--
作者:
Salerno, Michael;Sica, Christopher;Kramer, Christopher M.;Meyer, Craig H.
To develop and evaluate variable-density (VD) spiral first-pass perfusion pulse sequences for improved efficiency and off-resonance performance and to demonstrate the utility of an apodizing density compensation function (DCF) to improve SNR and reduce dark-rim artifact caused by cardiac motion and Gibbs Ringing. Three variable density spiral trajectories were designed, simulated, and evaluated in 18 normal subjects, and in 8 patients with cardiac pathology on a 1.5T scanner. By utilizing a density compensation function (DCF) which intentionally apodizes the k-space data, the side-lobe amplitude of the theoretical PSF is reduced by 68%, with only a 13% increase in the FWHM of the main-lobe as compared to the same data corrected with a conventional VD DCF, and has an 8% higher resolution than a uniform density spiral with the same number of interleaves and readout duration. Furthermore, this strategy results in a greater than 60% increase in measured SNR as compared to the same VD spiral data corrected with a conventional DCF (p<0.01). Perfusion defects could be clearly visualized with minimal off-resonance and dark-rim artifacts. VD spiral pulse sequences using an apodized DCF produce high-quality first-pass perfusion images with minimal dark-rim and off-resonance artifacts, high SNR and CNR and good delineation of resting perfusion abnormalities.
登录
查看更多内容
影响因子:
3.3
作者:
Di Bella, EVR;Parker, DL;Sinusas, AJ
通讯作者:
Sinusas, AJ
影响因子:
3.8
作者:
PARKER, DL;GULLBERG, GT;FREDERICK, PR
通讯作者:
FREDERICK, PR
影响因子:
37.8
作者:
Berrington de Gonzalez A;Kim KP;Smith-Bindman R;McAreavey D
通讯作者:
McAreavey D
影响因子:
3.3
作者:
Chen, Weitian;Meyer, Craig H.
通讯作者:
Meyer, Craig H.
影响因子:
3.3
作者:
Morrell, G;Macovski, A
通讯作者:
Macovski, A