New biomedical approaches for sexually transmitted infection prevention: vaccines and microbicides.
New biomedical approaches for sexually transmitted infection prevention: vaccines and microbicides.
复制标题
预防性传播感染的新生物医学方法：疫苗和杀菌剂。
DOI：
10.1016/j.admecli.2004.02.010
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Rosenthal,SusanL
中科院分区：
文献类型：
--
作者：
Rupp,Richard;Stanberry,LawrenceR;Rosenthal,SusanL
Sexually transmitted infections (STIs), including HIV/AIDS, are major global public health problems. In the United States it is estimated that more than 12 million people are infected with STIs each year [1] and worldwide the number of HIV-infected people exceeds 42 million [2]. Each year approximately 3 million adolescents acquire an STI and one in four sexually experienced adolescents will acquire an STD by the time they are l8 years of age [3]. Articles elsewhere in this issue discuss epidemiology and the manifestations and sequelae of each patho-gen. Current strategies of abstinence, monogamy, condom use, and partner notification and treatment are having an effect, but may not be sufficient to stem the tide of the STI epidemic.The development of additional biomedical prevention strategies, such as vaccines and topical microbicides, holds promise for the future. Vaccination will be effective only if there is widespread uptake, however, and microbicides only if they are used consistently and correctly. Thus, even new biomedical strategies will require behavioral interventions. This article reviews the status of vaccine and topical microbicide development and the issues that will be associated with adolescent acceptance of these new methods.
