Optimal follow-up time after continuous renal replacement therapy in actual renal failure patients stratified with the RIFLE criteria
Optimal follow-up time after continuous renal replacement therapy in actual renal failure patients stratified with the RIFLE criteria
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DOI：
10.1093/ndt/gfh581
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发表时间：
2005-02-01
影响因子：
6.1
通讯作者：
Martling, CR
中科院分区：
文献类型：
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作者：
Bell, M;Liljestam, E;Martling, CR
背景我们希望确定接受连续性肾脏替代疗法（CRRT）治疗的急性肾衰竭（ARF）患者的最佳随访持续时间，并检验以下假设：6个月随访是发现大多数死亡率的最短时间。此外，我们还评估了同一患者的死亡率与步枪分类之间的相关性。我们分析了1995年至2001年期间8152名连续入住瑞典大学医院重症监护室（ICU）的患者的数据。在人口中，207例患者接受了CRRT治疗，排除16例非肾脏适应症治疗。该队列的ICU死亡率分别为34.8%和30天，住院死亡率分别为45.9%和50.2%。该队列在入选后6个月的全因死亡率为59.9%，但54.6%早在60天后死亡。在更严重的步枪类别中，F（失败）患者的30天死亡率为57.9%，而RIFLE-R（风险）类别中的患者为23.5%，RIFLE-I（损伤）患者为22.0%。我们认为，60天随访足以发现接受CRRT治疗的ARF患者中的大多数死亡。RIFLE-F类患者的死亡率显著高于RIFLE-R和-1类患者。
Background. We wished to determine the optimal duration of follow-up For patients with acute renal failure (ARF) treated with Continuous renal replacement therapy (CRRT) and tested the hypothesis that a 6 month follow-up would be the minimum to catch most of the mortalities. In addition, we evaluated the association between mortality and the RIFLE classification in the same patients.Methods. We analysed the data of 8152 consecutive patients who had been admitted to the intensive care unit (ICU) of a Swedish university hospital between 1995 and 2001. Of that population., 207 patients were treated with CRRT, excluding 16 treated for non-renal indications.Results. ICU mortality in this cohort was 34.8% and 30 day and in-hospital mortalities were 45.9% and 50.2%, respectively. The cohort's all-cause mortality 6 months after inclusion was 59.9%, but 54.6% died as early as after 60 days. Patients in the more severe RIFLE category, F (failure), had a 30 day mortality of 57.9% compared with 23.5% for those in the RIFLE-R (risk) category and 22.0% for RIFLE-I (injury) patients.Conclusions. In our opinion, a 60 day follow-up is sufficient to catch the majority of deaths in ARF patients treated with CRRT. The patients in the RIFLE-F category had a significantly higher mortality than RIFLE-R and -1 patients.