THE IDENTIFICATION OF 5-HYDROXY-L-NORVALINE IN CULTURES OF PYRIDOXINE AUXOTROPHS OF ESCHERICHIA-COLI-B
THE IDENTIFICATION OF 5-HYDROXY-L-NORVALINE IN CULTURES OF PYRIDOXINE AUXOTROPHS OF ESCHERICHIA-COLI-B
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DOI：
10.1021/np50098a007
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发表时间：
1993-08-01
影响因子：
5.1
通讯作者：
SMITH, KC
中科院分区：
文献类型：
--
作者：
HILL, RE;WHITE, RL;SMITH, KC
Gc-ms and hplc have been employed to identify 5-hydroxy-L-norvaline (L-2-amino-5-hydroxypentanoic acid) in the culture fluids of pyridoxine-starved cultures of two pyridoxine auxotrophs of Escherichia coli B. The production of 5-hydroxynorvaline is shown to be secondary to pyridoxine starvation of the cultures, and the quantities of 5-hydroxynorvaline are similar to those of the common protein amino acids present in these cultures. This is the first time that 5-hydroxynorvaline has been identified as a product of bacterial metabolism.
