An in situ silver cationization method for hydrocarbon mass spectrometry
An in situ silver cationization method for hydrocarbon mass spectrometry
复制标题
DOI：
10.1016/j.jasms.2004.12.011
复制
发表时间：
2005-04-01
影响因子：
3.2
通讯作者：
deVries, MS
中科院分区：
文献类型：
--
作者：
Grace, LI;Abo-Riziq, A;deVries, MS
我们开发了一种新的阳离子化方法，用于紫外激光解吸质谱分析长链烃。在这种技术中，我们在样品上电喷涂一层薄薄的AgNO3涂层，并进行紫外激光解吸，以产生样品分子的Ag+阳离子化。在我们的显微镜/TOF-MS中使用这种技术使我们能够确定样品中检测到的物种的空间分布。我们演示了8亩的空间分辨率，原则上可以实现亚微米分辨率。在含有芳香族和脂肪族化合物的混合样品中，芳香族化合物直接电离，不形成加合物，因此给出单峰，而不是银阳离子的双峰。这样可以区分同一样品中的芳香族和脂肪族化合物。（J Am Soc质谱，2005,16,437-440）(c) 2005美国质谱学会
We have developed a novel cationization method for the analysis of long-chain hydrocarbons via UV laser desorption mass spectrometry. In this technique we electrospray a thin coating of AgNO3 over a sample and perform UV laser desorption to produce Ag+ cationization of sample molecules. Use of this technique in our microscope/TOF-MS allows us to determine the spatial distribution of the species we detect in the sample. We demonstrate 8-mu spatial resolution, and submicron resolution is possible in principle. In mixed samples containing aromatic and aliphatic compounds, the aromatic compounds ionize directly and do not form adducts, and thus give single peaks as opposed to doublets from silver cations. This enables distinction between aromatic and aliphatic compounds that are in the same sample. (J Am Soc Mass Spectrom 2005, 16, 437-440) (c) 2005 American Society for Mass Spectrometry