Corneal power measurement with Fourier-domain optical coherence tomography.
Corneal power measurement with Fourier-domain optical coherence tomography.
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DOI：
10.1016/j.jcrs.2010.07.018
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发表时间：
2010-12
影响因子：
2.8
通讯作者：
Huang, David
中科院分区：
文献类型：
--
作者：
Tang, Maolong;Chen, Alex;Li, Yan;Huang, David
研究傅立叶域光学相干断层扫描（OCT）测量前、后和净角膜屈光力的准确性和可重复性。美国加州洛杉矶多希尼眼科研究所。横断面研究。采用傅立叶域OCT系统（RTVue）对正常眼、近视眼准分子激光原位角膜磨镶术（LASIK）后眼和圆锥角膜眼进行扫描。在描绘角膜表面之后，系统通过在中心3.0 mm直径区域上的曲线拟合来计算前角膜屈光力和后角膜屈光力。使用厚晶状体公式计算净角膜屈光力。通过同一次访视的3次测量值的合并标准差来评估计算的重复性。将净角膜屈光力值与标准自动角膜曲率测量（IOLMaster）进行比较。正常组、LASIK术后组和圆锥角膜组的傅立叶域OCT净角膜屈光力的重复性分别为0.19 D、0.26 D和0.30 D。傅立叶域OCT净角膜屈光力显著低于角膜曲率计，平均值分别为-1.21 D、-2.89 D和-3.07 D（P<.001）。LASIK术后和圆锥角膜患者的前后曲率比均低于正常眼（P<0.001）。在所有3组中，通过傅立叶域OCT测量的角膜屈光力均具有良好的重复性。重复性优于较慢的时域OCT系统。由于傅立叶域OCT直接测量角膜前表面和后表面，因此在LASIK术后和圆锥角膜患者中，其可产生比标准角膜曲率计更一致的结果，其中前-后角膜曲率比因手术或疾病而改变。
To study the accuracy and repeatability of anterior, posterior, and net corneal power measured by Fourier-domain optical coherence tomography (OCT). Doheny Eye Institute, Los Angeles, California, USA. Cross-sectional study. A Fourier-domain OCT system (RTVue) was used to scan normal eyes, eyes after myopic laser in situ keratomileusis (LASIK), and keratoconic eyes. After the corneal surfaces were delineated, the system calculated anterior and posterior corneal powers by curve fitting over the central 3.0 mm diameter area. Net corneal power was calculated using a thick-lens formula. The repeatability of the calculations was evaluated by the pooled standard deviation of 3 measurements from the same visit. The net corneal power values were compared with standard automated keratometry measurements (IOLMaster). The repeatability of Fourier-domain OCT net corneal power was 0.19 diopters (D), 0.26 D, and 0.30 D in the normal, post-LASIK, and keratoconus groups, respectively. The Fourier-domain OCT net corneal power was significantly lower than keratometry by a mean of −1.21 D, −2.89 D, and −3.07 D, respectively (P<.001). The anterior–posterior curvature ratio was lower in post-LASIK and keratoconic eyes than in normal eyes (P<.001). Corneal power measured by Fourier-domain OCT achieved good repeatability in all 3 groups. The repeatability was better than slower time-domain OCT systems. Because Fourier-domain OCT directly measures both anterior and posterior corneal surfaces, it may produce more consistent results than standard keratometry in post-LASIK and keratoconic eyes in which the anterior–posterior corneal curvature ratios are altered by surgery or disease.
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