Time to embrace PROMIS-29 as the standard health-related quality of life instrument for patients with cirrhosis.
Time to embrace PROMIS-29 as the standard health-related quality of life instrument for patients with cirrhosis.
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是时候采用 PROMIS-29 作为肝硬化患者健康相关生活质量的标准工具了。
DOI：
10.1097/hep.0000000000000508
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发表时间：
2023
期刊：
影响因子：
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通讯作者：
Lai,JenniferC
中科院分区：
文献类型：
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作者：
Tapper,ElliotB;Lai,JenniferC
肝硬化是一种常见和严重的疾病，其特点是身体和心理症状的高度负担。[1,2]健康相关生活质量（HRQOL）往往较差，因为这种症状负担是肝硬化患者未满足的关键需求。由于缺乏标准化的HRQOL筛查工具，表征肝硬化患者HRQOL缺陷的深度和广度的努力受到限制。这并不是说不存在——事实上，已有许多在肝硬化患者中进行的研究[1,3]——但肝病学领域缺乏的是围绕一种能够平衡广度、深度和实用性的单一工具达成共识，以便广泛用于肝硬化患者。围绕“最佳”HRQOL工具的困惑阻碍了前瞻性队列和临床试验中HRQOL测量的纳入，出版物中HRQOL报告的标准化以及临床护理的采用。
Cirrhosis is a common and serious illness characterized by a high burden of physical and psychological symptoms.[1, 2] Health-related quality of life (HRQOL) is often poor because of this symptom burden and represents a key unmet need for patients with cirrhosis. Efforts to characterize the depth and breadth of HRQOL deficits in patients with cirrhosis are limited by the lack of a standardized HRQOL screening tool. It is not that one does not exist—in fact, many have been studied in patients with cirrhosis [1, 3]—but what the hepatology field is lacking is consensus around a single instrument that balances breadth, depth, and pragmatism so that it can be widely used for patients with cirrhosis. Confusion around the “optimal” HRQOL tool has hampered the incorporation of HRQOL measures in prospective cohorts and clinical trials, standardization of HRQOL reporting in publications, and uptake in clinical care.