Acute in vivo Recording with a Generic Parylene Microelectrode Array Implanted with Dip-coating Method into the Rat Brain.

Acute in vivo Recording with a Generic Parylene Microelectrode Array Implanted with Dip-coating Method into the Rat Brain.
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使用浸涂法植入大鼠脑中的通用聚对二甲苯微电极阵列进行急性体内记录。

DOI：
10.1109/embc48229.2022.9870987
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发表时间：
2022
期刊：
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
影响因子：
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通讯作者：
Song,Dong
Song,Dong
中科院分区：
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文献类型：
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作者：
Xu,Huijing;Scholten,Kee;Jiang,Wenxuan;Ortigoza-Diaz,Jessica-Lizbeth;Lu,Zhouxiao;Liu,Xin;Meng,Ellis;Song,Dong

文献摘要

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Flexible polymer-based microelectrode arrays (MEAs) can reduce tissue inflammation and foreign body response and greatly prolong the lifetime of neural implants. However, standard and customized polymer devices are only accessible to limited groups. To better promote the development and application of polymer MEAs, we have launched the Polymer Implantable Electrode (PIE) Foundry and developed a 64-channel Parylene C-based MEA with generic electrodes layout that can be used to record from both cortical and sub-cortical regions in rodents. In addition, a practical dip-coating protocol for the insertion of the flexible standard Parylene MEA is developed.