Nuclear hormone receptors in podocytes.
Nuclear hormone receptors in podocytes.
复制标题
DOI:
10.1186/2045-3701-2-33
复制
发表时间:
2012-09-20
影响因子:
7.5
通讯作者:
Kao HY
中科院分区:
文献类型:
--
作者:
Khurana S;Bruggeman LA;Kao HY
Nuclear receptors are a family of ligand-activated, DNA sequence-specific transcription factors that regulate various aspects of animal development, cell proliferation, differentiation, and homeostasis. The physiological roles of nuclear receptors and their ligands have been intensively studied in cancer and metabolic syndrome. However, their role in kidney diseases is still evolving, despite their ligands being used clinically to treat renal diseases for decades. This review will discuss the progress of our understanding of the role of nuclear receptors and their ligands in kidney physiology with emphasis on their roles in treating glomerular disorders and podocyte injury repair responses.
登录
查看更多内容
影响因子:
20.3
作者:
Fisher, Cynthia L.;Pineault, Nicolas;Brock, Hugh W.
通讯作者:
Brock, Hugh W.
影响因子:
19.6
作者:
Doublier S;Lupia E;Catanuto P;Periera-Simon S;Xia X;Korach K;Berho M;Elliot SJ;Karl M
通讯作者:
Karl M
影响因子:
16
作者:
Bourguet, W;Vivat, V;Moras, D
通讯作者:
Moras, D
影响因子:
4.8
作者:
Chen, SY;Johnson, BA;Zhou, GC
通讯作者:
Zhou, GC
影响因子:
19.6
作者:
Collino, M;Patel, NSA;Thiemermann, C
通讯作者:
Thiemermann, C