VARIABILITY OF FVC AND FEV(1) DUE TO TECHNICIAN, TEAM, DEVICE AND SUBJECT IN AN 8-CENTER STUDY - 3 QUALITY-CONTROL STUDIES IN SAPALDIA
VARIABILITY OF FVC AND FEV(1) DUE TO TECHNICIAN, TEAM, DEVICE AND SUBJECT IN AN 8-CENTER STUDY - 3 QUALITY-CONTROL STUDIES IN SAPALDIA
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DOI：
10.1183/09031936.95.08030371
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发表时间：
1995-03-01
影响因子：
24.3
通讯作者：
ZEMP, E
中科院分区：
文献类型：
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作者：
KUNZLI, N;ACKERMANNLIEBRICH, U;ZEMP, E
在8个SAPALDIA（瑞士成人空气污染和肺部疾病研究）中心的随机人群样本的肺功能测试必须同时进行，在一年内，由8个团队和23名技术人员。我们进行了质量控制研究，以测试技术人员，团队和设备相关的系统测量误差。为了评估技术人员的效果，每个中心进行了一项研究，涉及12-19名受试者。两项研究（各有13名参与者）讨论了团队和设备的影响，在所有研究中，志愿者使用不同的技术人员或设备重复进行肺量测定，技术人员的影响，估计团队或设备八个团队中的“技术员"和”团队“都不能解释用力肺活量（FVC）或一秒用力呼气量（FEV（1））的显著差异.器械效应研究显示，由于试验日期间发生的技术问题，1号器械的PVC值降低了10%，但并非在主SAPALDIA研究中，进一步调查显示了经过培训的技术人员无法识别的潜在硬件和软件错误源。这些研究没有证据表明在主SAPALDIA研究期间技术人员、团队或器械导致系统性错误，但是，他们揭示了现代设备中潜在的错误来源，这些设备的功能就像“黑匣子”，制造商应该改进肺活量测定软件，以进一步提高技术人员对准确评估的尝试。
Lung function testing of a random population sample in the eight SAPALDIA (Swiss study on air pollution and lung diseases in adults) centres had to be performed simultaneously, within one year, by eight teams and 23 technicians, We conducted quality control studies to test for technician, team and device related systematic measurement errors.To assess technician effects, each centre conducted a study involving 12-19 subjects. Two studies with 13 participants each addressed team and device effects, In all studies, volunteers repeatedly performed spirometry with different technicians or devices, Effects due to technician, team or device were estimated (analysis of variance).Neither ''technician'' within any of eight teams nor ''team'' accounted for significant differences of forced vital capacity (FVC) or forced expiratory volume in one second (FEV(1)). The Device Effect Study revealed 10% lower PVC values for device No, 1 due to a technical problem occurring during the test day but not in the main SAPALDIA study, Further investigations revealed potential hardware and software sources of error which are not recognizable by trained technicians.These studies gave no evidence for systematic errors due to technician, team or device during the main SAPALDIA study, However, they revealed potential sources of error in modern devices, which function as ''black boxes'', Manufacturers should improve spirometry software to further enhance the technicians' attempts at accurate assessment.