Ultraconservation of enhancers is not ultranecessary.
Ultraconservation of enhancers is not ultranecessary.
复制标题
增强子的过度保守并不是绝对必要的。
DOI：
10.1038/s41588-021-00839-6
复制
发表时间：
2021
期刊：
影响因子：
30.8
通讯作者：
Pollard,KatherineS
中科院分区：
文献类型：
--
作者：
Pittman,Maureen;Pollard,KatherineS
Stretches of non-coding DNA that have remained identical across millions of years of evolution are typically assumed to have functional regulatory roles that would be compromised by any amount of nucleotide substitution. A new study finds that these ultraconserved regions are more robust to mutagenesis than their level of conservation would suggest.
