Radiofrequency ablation of hypertrophic obstructive cardiomyopathy - a potential method for clinical application
Radiofrequency ablation of hypertrophic obstructive cardiomyopathy - a potential method for clinical application
复制标题
肥厚型梗阻性心肌病的射频消融——一种潜在的临床应用方法
DOI：
10.1016/j.ijcard.2022.08.003
复制
发表时间：
2022
影响因子：
3.5
通讯作者：
Yanmei Lu
中科院分区：
文献类型：
--
作者：
Huasheng Lv;Yongqiang Fan;Meidina Yeerken;Liang Gao;Baopeng Tang;Yanmei Lu
肥厚型心肌病（HCM）是一种以左心室心肌肥厚为特征的心脏疾病，其原因是编码肌球蛋白的基因突变或未知的遗传变异，临床患病率为1：500至1：200 [1]。肥厚型心肌病最容易引起左心室流出道（LVOT）梗阻，称为肥厚型梗阻性心肌病（HOCM）。HOCM的治疗旨在降低左室流出道压力梯度，缓解症状。
Hypertrophic cardiomyopathy (HCM) is a cardiac disease characterized by left ventricular myocardial hypertrophy due to a mutation in the gene encoding myosin, or an unknown genetic variant, with a prevalence ranging from 1:500 to 1:200 in clinics [1. HCM is most likely to cause left ventricular outflow tract (LVOT) obstruction, which is known as hypertrophic obstructive cardiomyopathy (HOCM). The treatment of HOCM is aiming to reduce left ventricular outflow tract pressure gradient and relieve symptoms.