BMI rebound, childhood height and obesity among adults: the Bogalusa Heart Study

BMI rebound, childhood height and obesity among adults: the Bogalusa Heart Study
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DOI:
10.1038/sj.ijo.0801581
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发表时间:
2001-04-01
影响因子:
4.9
通讯作者:
Berenson, GS
Berenson, GS
中科院分区:
医学2区
文献类型:
--
作者:
Freedman, DS;Khan, LK;Berenson, GS

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目的:婴儿出生后体重指数(BMI,kg/m(2))开始上升被称为肥胖反弹,多项研究发现,早期反弹会增加成年后超重的风险。我们检验了这种关系是否独立于儿童BMI水平。设计:一项对105名受试者在5、6、7、8和19-23岁进行检查的纵向研究。结果:BMI反弹年龄(Min)小于或等于5岁的受试者在成年早期平均比年龄(Min)大于或等于7岁(Min)的受试者重4-5 kg/m(2),但也与儿童BMI水平相关(r类似于-0.5),我们发现,如果7岁(或8岁)的BMI水平已知,年龄(分钟)并不能提供成人超重的额外信息。相反,童年身高也与年龄(分钟)相关(r=-0.47),与成年BMI独立相关。在体重相对较重(BMI=16.0 kg/m(2))的5岁儿童中,成年后身高120 cm的儿童估计比身高104 cm的儿童重1.2 kg/m(2)。结论:尽管早期BMI反弹与成年后较高的相对体重水平有关,但这种联系并不独立于儿童BMI水平。童年身高与成年BMI的关系需要在其他队列中得到证实,但童年身高可能有助于识别可能成为超重成年人的儿童。
OBJECTIVE: The beginning of the post-infancy rise in the body mass index (BMI, kg/m(2)) has been termed the adiposity rebound, and several studies have found that an early rebound increases the risk for overweight in adulthood. We examined whether this relation is independent of childhood BMI levels.DESIGN: A longitudinal study of 105 subjects who examined at ages 5, 6, 7, 8 and 19-23 y.RESULTS: Subjects with an age at the BMI rebound (age(min)) of less than or equal to 5 y were, on average, 4-5 kg/m(2) heavier in early adulthood than were subjects whose age(min) was greater than or equal to 7Y Age(min), however, was also correlated with childhood BMI levels (r similar to -0.5), and we found that age(min) provided no additional information on adult overweight if the BMI level at age 7 y (or 8 y) was known. In contrast, childhood height, which was also correlated with age(min) (r= -0.47), was independently related to adult BMI. Among relatively heavy (BMI=16.0kg/m(2)) 5-y-olds, a child with a height of 120cm was estimated to be 1.2kg/m(2) heavier in adulthood than would a 104 cm tall child.CONCLUSIONS: Although an early BMI rebound was related to higher levels of relative weight in adulthood, this association was not independent of childhood BMI levels. The relation of childhood height to adult BMI needs to confirmed in other cohorts, but it is possible that childhood height may help identify children who are likely to become overweight adults.