Primary pituitary lymphoma in an immunocompetent patient: a rare clinical entity
Primary pituitary lymphoma in an immunocompetent patient: a rare clinical entity
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免疫功能正常患者的原发性垂体淋巴瘤：一种罕见的临床实体
DOI：
10.1007/s00415-011-6179-6
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发表时间：
2012-02-01
影响因子：
6
通讯作者：
Chen, Ni
中科院分区：
文献类型：
--
作者：
Li, Yaxiong;Zhang, Yuekang;Chen, Ni
原发性垂体淋巴瘤在免疫功能正常的病人是一个非常罕见的临床实体。我们报告的情况下，一个41岁的妇女与初始多饮和多尿。当实验室评估显示全垂体功能减退时，进行了垂体增强MRI，提示垂体腺瘤。在观察过程中，也证实了鞍区肿块扩大引起的阻塞性脑积水，并在病变切除后进行了分流手术。组织学检查和免疫表型证实弥漫性大B细胞非霍奇金淋巴瘤。患者分期时未发现全身性疾病。我们还将回顾自1993年以来报道的28例病例的临床、放射学特征和结局。
Primary pituitary lymphoma in immunocompetent patients is an exceedingly rare clinical entity. We report the case of a 41-year-old woman with initial polydipsia and polyuria. When laboratory evaluation revealed panhypopituitarism, a pituitary enhanced MRI was performed and was suggestive of a pituitary adenoma. Obstructive hydrocephalus provoked by enlarged sellar mass was also demonstrated during observation, and a shunt procedure following lesion resection was carried out. Histopathological examination and immunophenotyping verified diffuse large B-cell non-Hodgkin's lymphoma. No systemic disease was found on staging of the patient. We will also review the clinical, radiological features and outcomes of 28 cases that have been reported since 1993.