Solvatochromic solvent polarity measurements and selectivity in reversed-phase liquid chromatography.
Solvatochromic solvent polarity measurements and selectivity in reversed-phase liquid chromatography.
复制标题
反相液相色谱中的溶剂变色溶剂极性测量和选择性。
DOI：
10.1016/s0021-9673(01)94673-4
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Dorsey,JG
中科院分区：
文献类型：
--
作者：
Johnson,BP;Khaledi,MG;Dorsey,JG
测定了反相液相色谱中乙腈-水和甲醇-水二元移动的流动相的ET（30）极性值，并与传统硅键合相和聚苯乙烯-二乙烯苯树脂反相材料的亚甲基选择性（α CH 2）进行了比较。发现两者的亚甲基选择性的变化与甲醇-水混合物中有机溶剂的百分比最相关，而ET（30）极性在乙腈-水混合物中提供了最好的相关性。发现聚合物树脂柱在所有浓度的有机溶剂下提供比硅质键合相更高的亚甲基选择性。
TheET(30) polarity values of binary acetonitrile—water and methanol—water mobile phases, used in reversed-phase liquid chromatography, were measured and compared with methylene selectivity (αCH2for both traditional siliceous bonded phases and for a polystyrene—divinylbenzene resin reversed-phase material. The variation in methylene selectivity for both was found to correlate best with percent organic solvent in methanol—water mixtures, while theET(30) polarity provided the best correlation in acetonitrile—water mixtures. The polymeric resin column was found to provide higher methylene selectivity than the siliceous bonded phase at all concentrations of organic solvent.