Harry A. Fozzard, MD: 1931–2014.
Harry A. Fozzard, MD: 1931–2014.
复制标题
Harry A. Fozzard，医学博士：1931 年至 2014 年。
DOI：
10.1161/circresaha.115.306038
复制
发表时间：
2015
影响因子：
20.1
通讯作者：
January,CraigT
中科院分区：
文献类型：
--
作者：
Kamp,TimothyJ;January,CraigT
芝加哥大学医学系荣誉退休教授、前《循环研究》主编，于2014年12月9日在睡梦中逝世，享年83岁。福扎德博士的职业生涯和生活反映了心脏电生理学作为研究和临床学科的出现和发展。值得注意的是，反思心脏电生理学方面的进展以及Fozzard在这些进展中所起的相互交织的作用。1福扎德博士曾就读于圣路易斯华盛顿大学医学院，在那里他有幸在伯爵萨瑟兰的实验室获得了他的第一次认真的研究经验。萨瑟兰伯爵是未来的诺贝尔奖获得者，他发现了腺苷环化酶和cAMP作为第二个信使系统。这引发了Fozzard对细胞膜及其相关信号通路的兴趣。随后，他在耶鲁大学实习，然后在美国海军医疗队服役。他回到了华盛顿大学，在那里他完成了内科住院医师和心脏病学培训。Fozzard博士对膜蛋白的研究最初集中在Na/K ATAPase上，这导致了1964年他的第一个
Service Professor Emeritus in the Department of Medicine at the University of Chicago and former editor-inchief of Circulation Research, passed away in his sleep on December 9, 2014 at the age of 83. Dr Fozzard’s career and life reflected the emergence and evolution of cardiac electrophysiology as research and clinical disciplines. It is remarkable to reflect on the advances that have occurred in cardiac electrophysiology and the interwoven role Fozzard played in those advances. 1Dr Fozzard attended medical school at Washington University in St. Louis where he had the good fortune of having his first serious research experience in the laboratory of Earl Sutherland, a future Nobel Prize winner for the discovery of adenylyl cyclase and cAMP as a second messenger system. This triggered Fozzard’s interest in the cell membrane and associated signaling pathways. He subsequently did his internship at Yale University before serving in the US Navy Medical Corps. He returned to Washington University where he completed his internal medicine residency and cardiology training. Dr Fozzard’s research on membrane proteins initially focused on the Na/K ATAPase which resulted in 1964 in his first