Proceedings of the Inaugural Pediatric Dermatology Research Alliance (PeDRA) conference.
Proceedings of the Inaugural Pediatric Dermatology Research Alliance (PeDRA) conference.
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首届儿童皮肤病学研究联盟 (PeDRA) 会议论文集。
DOI：
10.1038/jid.2014.227
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Paller,AmyS
中科院分区：
文献类型：
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作者：
Siegel,DawnH;Choate,KeithA;Drolet,BethA;Frieden,IlonaJ;Rittenberg,Sheila;Teng,JoyceM;Tom,WynnisL;Williams,MaryL;Eichenfield,LawrenceF;Paller,AmyS
涉及儿童的皮肤病研究目前面临几个主要障碍。因此，许多治疗方法仅适用于儿童，而我们儿科人群中许多最紧迫的临床需求仍未得到解决。儿科皮肤病学会(SPD)的一个战略规划委员会确定了需要一个有组织的、包容性的研究联盟，以增加个人从业者和先前存在的较小合作小组的资源，并促进强大的、多中心的、转化性和临床研究和治疗试验。2011年12月，国家关节炎、肌肉骨骼和皮肤病研究所(NIAMS)的儿科皮肤病圆桌会议进一步详细说明了将科学进步转化为临床实践的治疗差距和障碍。在这些论坛的基础上，2012年7月，一组感兴趣的研究人员在加利福尼亚州蒙特利会面，为合作的儿科皮肤研究开发基础设施，现在称为儿科皮肤病研究联盟(Pedra)。Pedra的愿景是创建可持续的合作研究网络，以更好地了解、预防、治疗和治愈儿童皮肤病。在此基础上，增加了小组委员会和专家成员，确定了利益攸关方，获得了种子资金，并于2013年10月在伊利诺伊州芝加哥举行了第一次Pedra独立研究会议。
Skin disease research involving children currently faces several major hurdles. As a result, many therapies are only available for off-label use in children, and many of the most pressing clinical needs of our pediatric population remain unsolved. A strategic planning committee of the Society for Pediatric Dermatology (SPD) identified the need for an organized, inclusive research alliance to augment the resources of individual practitioners and preexisting smaller collaborative groups and facilitate robust, multicenter-based, translational and clinical research and therapeutic trials. A December 2011 National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Roundtable on Pediatric Dermatology further detailed the therapeutic gaps and barriers to translation of scientific advances to clinical practice. Building on these forums, in July 2012, a group of interested investigators met in Monterey, CA, to develop the infrastructure for collaborative pediatric skin research, now called the Pediatric Dermatology Research Alliance (PeDRA). The vision of PeDRA is to create sustainable collaborative research networks to better understand, prevent, treat, and cure dermatologic diseases in children. From that starting point, subcommittees and expert members were added, stakeholders were identified, and seed funding was garnered, with the first PeDRA stand-alone research meeting realized in Chicago, IL, in October 2013.