Fast fragmenting mitochondria by TORC2.
Fast fragmenting mitochondria by TORC2.
复制标题
TORC2 快速裂解线粒体。
DOI:
10.1038/s41556-023-01173-1
复制
发表时间:
2023
影响因子:
21.3
通讯作者:
Mair,WilliamB
中科院分区:
文献类型:
--
作者:
Valera-Alberni,Miriam;Mair,WilliamB
Mitochondria are dynamic organelles, changing their morphology and functional capacity in response to physiological and metabolic cues. A study uncovers a role for the typically nutrient-responsive mTORC2 during fasting in vivo to promote mitochondrial fission via the activation of a signalling pathway that involves NDRG1 and CDC42.