Sensory representation in the cerebellum of the catfish
Sensory representation in the cerebellum of the catfish
复制标题
鲶鱼小脑的感觉表征
DOI：
10.1016/0306-4522(84)90266-5
复制
发表时间：
1984
期刊：
影响因子：
3.3
通讯作者：
T. Bullock
中科院分区：
文献类型：
--
作者：
L. Lee;T. Bullock
用生理刺激、外周神经电击和大脑中央结构电击研究了鲶鱼小脑的感觉表征。在小脑不同部位记录诱发场电位和单位反应。在鲶鱼中，不同的感觉方式是由离散的，只有部分重叠的小脑区域。根据目前的标准，大多数单位是单峰的;只有在瓣膜中，一小部分单位对两种或更多种方式有反应。视觉和躯体感觉区是最大的，它们占据了小脑体和瓣膜的大部分。在躯体中，大多数视觉单位位于中线附近和背侧层，而躯体感觉单位则位于更外侧和腹侧。机械侧线输入在颗粒隆起和瓣膜中表现。在瓣膜中发现了声学单位。电感受单位记录从外侧叶尾侧，并在较小程度上，从隆起颗粒和瓣膜。正弦倾斜和振动单位位于尾叶内侧部。单位的感受野，无论形式如何，通常都是大而弥散的。有些视觉单位对移动的物体反应最好。感受野的地形结构只存在于躯体感觉单位之间。除了这些通道分离的发现，比较神经学感兴趣的特征如下。大多数单位可识别为浦肯野细胞，具有典型的苔藓纤维颗粒细胞模式，但与大多数哺乳动物的经验相反，在对直接脑或神经刺激的反应中，简单的棘波对不同的模式有不同的动态反应。有些人首先兴奋，然后抑制，其他人反之亦然。有些单位对我们提供的任何感官输入都没有反应。一些不符合浦肯野细胞标准的单位符合宽枝细胞的几个标准;它们产生大的尖峰，并在相对长的潜伏期后受到感觉刺激的影响。然而，仅在某些视觉单位中始终观察到复杂的尖峰。
Sensory representation in the catfish cerebellum was studied with physiological stimuli, with electric shocks applied to peripheral nerves and with electric shocks to central structures of the brain. Evoked field potentials and unit responses were recorded in different places in the cerebellum. In the catfish, different sensory modalities are represented by discrete, only partly overlapping areas of the cerebellum. Most units are unimodal by present criteria; only in the valvula a fraction of the units are responsive to two or more modalities. Visual and somatosensory areas are the largest and they occupy the bulk of the corpus cerebelli and the valvula. In the corpus, most of the visual units are near the midline and in the dorsal tier while the somatosensory units are more lateral and ventral. Mechanical lateral line input is represented in the eminentia granularis and the valvula. Acoustic units are found in the valvula. Electroreceptive units are recorded from the lateral lobus caudalis, and to a lesser degree, from the eminentia granularis and valvula. Sinusoidal tilting and vibration units are in the lobus caudalis pars medialis. Receptive fields of units, regardless of modality, are generally large and diffuse. Some visual units respond best to moving objects. Topographical organization of receptive fields only exists among the somatosensory units.Besides these findings of modality segregation, the features of interest for comparative neurology are the following. Most units are identifiable as Purkinje cells with a characteristic mossy fiber-granular cell pattern, and but in contrast to most experience with mammals, in response to direct brain or nerve stimulations, the simple spikes have different dynamic responses for different modalities. Some are first excited, then inhibited, others vice versa. Some units are not responsive to any sensory input we delivered. Some units not meeting the criteria for Purkinje cells meet several criteria for eurydendroid cells; they give large spikes and are influenced by sensory stimuli after relative long latencies. Complex spikes, however, were only consistently observed in some of the visual units.