A cognitive map for object memory in the hippocampus
A cognitive map for object memory in the hippocampus
复制标题
DOI：
10.1101/lm.1484509
复制
发表时间：
2009-10-01
影响因子：
2
通讯作者：
Eichenbaum, Howard
中科院分区：
文献类型：
--
作者：
Manns, Joseph R.;Eichenbaum, Howard
海马被认为是支持认知地图的，它是对环境空间布局以及在该环境中遇到的非空间项目的心理表征。在本研究中，我们同时记录了从43至61海马锥体细胞大鼠进行的对象识别记忆任务中，新的和重复的对象在不同的位置上遇到一个圆形的轨道。神经数据的多变量分析表明，对象身份的信息表示次要的主要信息维度的对象位置。此外，神经数据与再认记忆任务的表现有关。结果表明，物体在海马认知地图上被表示为兴趣点，并且该地图在记住在特定位置遇到特定物体时很有用。
The hippocampus has been proposed to support a cognitive map, a mental representation of the spatial layout of an environment as well as the nonspatial items encountered in that environment. In the present study, we recorded simultaneously from 43 to 61 hippocampal pyramidal cells as rats performed an object recognition memory task in which novel and repeated objects were encountered in different locations on a circular track. Multivariate analyses of the neural data indicated that information about object identity was represented secondarily to the primary information dimension of object location. In addition, the neural data related to performance on the recognition memory task. The results suggested that objects were represented as points of interest on the hippocampal cognitive map and that this map was useful in remembering encounters with particular objects in specific locations.