CONGENITAL HEART-DISEASE - PREVALENCE AT LIVEBIRTH - THE BALTIMORE WASHINGTON INFANT STUDY
CONGENITAL HEART-DISEASE - PREVALENCE AT LIVEBIRTH - THE BALTIMORE WASHINGTON INFANT STUDY
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DOI：
10.1093/oxfordjournals.aje.a113979
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发表时间：
1985-01-01
影响因子：
5
通讯作者：
DOWNING, JW
中科院分区：
文献类型：
--
作者：
FERENCZ, C;RUBIN, JD;DOWNING, JW
巴尔的摩[美国马里兰州]-华盛顿[美国哥伦比亚特区]婴儿研究是一项先天性心脏病的地区性流行病学研究。在1981年和1982年出生在研究地区的婴儿中，664人在出生1岁时通过超声心动图、心导管插入术、心脏手术或尸检确诊为先天性心脏病。所有病例的患病率为3.7/1000活产儿，仅经侵入性方法确诊的活产儿患病率为2.4/1000。先天性心脏病的诊断特异性患病率与以前的8个病例系列进行了比较。在所涵盖的时间跨度内改变诊断分类，以及方法上的差异导致数据的巨大差异。使用相同病例发现方法的新英格兰[美国]婴儿心脏计划的数据显示，主要形态异常的发生情况相似，这表明这些是美国东部稳定的基本估计。在所有病例系列中，在40年的时间跨度中，确诊的先天性心脏病的发生率为千分之四。
The Baltimore [Maryland, USA]-Washington [District of Columbia, USA] Infant Study is a regional epidemiologic study of congenital heart disease. Among infants born in the study area in 1981 and 1982, 664 had a diagnosis of congenital heart disease confirmed in the 1st yr of life by echocardiography, cardiac catheterization, cardiac surgery or autopsy. The prevalence rate was 3.7/1000 livebirths for all cases and 2.4/1000 livebirths for cases confirmed by invasive methods only. Diagnosis-specific prevalence rates of congenital heart disease were compared with those of 8 previous case series. Changing diagnostic categorizations in the time span covered and methodological differences resulted in great variation of the data. The data of the New England [USA] Infant Cardiac Program which used the same case discovery methods showed similar occurrences of major morphologic abnormalities, suggesting that these were stable basic estimates in the eastern USA. For all case series, the rate of confirmed congenital heart disease was 4/1000 livebirths over the 40 yr time span.