Cranberries and cranberry products: Powerful in vitro, ex vivo, and in vivo sources of antioxidants
Cranberries and cranberry products: Powerful in vitro, ex vivo, and in vivo sources of antioxidants
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DOI：
10.1021/jf073309b
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发表时间：
2008-07-23
影响因子：
6.1
通讯作者：
Samman, Najwa
中科院分区：
文献类型：
--
作者：
Vinson, Joe A.;Bose, Pratima;Samman, Najwa
蔓越莓产品，特别是蔓越莓汁（CJ）已被消耗的健康原因，主要是由于其对尿路感染的影响。我们调查了数量的自由和总（水解后）酚类抗氧化剂的蔓越莓产品使用福林测定。以鲜重计，蔓越莓类食品中总多酚含量的顺序为：干制品>冷冻制品>酱制品>果冻酱料。在所有蔓越莓产品的食用量基础上，顺序如下：冷冻> 100%果汁>干燥> 27%果汁>酱料>果冻状酱料。高果糖玉米糖浆（HFCS）是美国糖消费的主要来源，含有葡萄糖和果糖，氧化应激的潜在介质。我们研究了HFCS和抗坏血酸与CJ抗氧化剂或没有CJ（对照）的消费的影响，给予10个正常人后，一夜之间的快速。血浆抗氧化能力，葡萄糖，甘油三酯，和抗坏血酸测定6次后7小时内消费的一个单一的240毫升的两种不同的饮料。控制HFCS引起血浆抗氧化能力在所有时间点略有下降，因此，尽管存在抗坏血酸氧化应激。CJ产生了血浆抗氧化能力的增加，在所有时间点均显著大于对照HFCS。餐后甘油三酯，由于果糖饮料，主要负责的氧化应激，并显着相关的氧化应激所测量的抗氧化能力。蔓越莓是优质抗氧化剂的极好来源，应在人体补充研究中进行检查。
Cranberry products and especially cranberry juice (CJ) have been consumed for health reasons primarily due to their effect on urinary tract infections. We investigated the quantity of both free and total (after hydrolysis) phenolic antioxidants in cranberry products using the Folin assay. The order of amount of total polyphenols in cranberry foods on a fresh weight basis was as follows: dried > frozen > sauce > jellied sauce. On a serving size basis for all cranberry products, the order was as follows: frozen > 100% juice > dried > 27% juice > sauce > jellied sauce. High fructose corn syrup (HFCS) is a major source of sugar consumption in the U.S. and contains both glucose and fructose, potential mediators of oxidative stress. We investigated the effect of the consumption of HFCS and ascorbate with CJ antioxidants or without CJ (control) given to 10 normal individuals after an overnight fast. Plasma antioxidant capacity, glucose, triglycerides, and ascorbate were measured 6 times over 7 h after the consumption of a single 240 mL serving of the two different beverages. The control HFCS caused a slight decrease in plasma antioxidant capacity at all time points and thus an oxidative stress in spite of the presence of ascorbate. CJ produced an increase in plasma antioxidant capacity that was significantly greater than control HFCS at all time points. Postprandial triglycerides, due to fructose in the beverages, were mainly responsible for the oxidative stress and were significantly correlated with the oxidative stress as measured by the antioxidant capacity. Cranberries are an excellent source of high quality antioxidants and should be examined in human supplementation studies.