Ebolavirus vaccines for humans and apes
Ebolavirus vaccines for humans and apes
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DOI：
10.1016/j.coviro.2012.04.003
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发表时间：
2012-06-01
影响因子：
5.9
通讯作者：
Sullivan, Nancy J.
中科院分区：
文献类型：
--
作者：
Fausther-Bovendo, Hugues;Mulangu, Sabue;Sullivan, Nancy J.
由于高病死率、人与人之间的传播以及可能用于生物恐怖主义，埃博拉病毒疫苗的开发仍然是当务之急。尽管目前没有获得许可的埃博拉病毒疫苗或治疗方法，但在对策的临床前测试方面取得了进展。在这里，我们将回顾埃博拉病毒候选疫苗及其在人类和野生类人猿中使用的考虑因素。
Because of high case fatality proportions, person-to-person transmission, and potential use in bioterrorism, the development of a vaccine against ebolavirus remains a top priority. Although no licensed vaccine or treatment against ebolavirus is currently available, progress in preclinical testing of countermeasures has been made. Here, we will review ebolavirus vaccine candidates and considerations for their use in humans and wild apes.