Rational tangle surgery and Xer recombination on catenanes

Rational tangle surgery and Xer recombination on catenanes
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DOI:
10.2140/agt.2012.12.1183
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发表时间:
2012-01-01
影响因子:
0.7
通讯作者:
Shimokawa, Koya
Shimokawa, Koya
中科院分区:
数学3区
文献类型:
--
作者:
Darcy, Isabel K.;Ishihara, Kai;Shimokawa, Koya

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蛋白质重组酶可以改变环状DNA的结型。重组酶将一个结转化为另一个结的作用通常通过带手术进行数学建模。对2桥结N(4 mn-1/2 m)上的带环手术进行表征,产生(2,2k)-环面连接。我们应用这个和其他合理的缠结手术的结果来分析Xer重组的DNA链使用缠结模型蛋白结合的DNA。
The protein recombinase can change the knot type of circular DNA. The action of a recombinase converting one knot into another knot is normally mathematically modeled by band surgery. Band surgeries on a 2-bridge knot N(4mn-1/2m) yielding a (2, 2k)-torus link are characterized. We apply this and other rational tangle surgery results to analyze Xer recombination on DNA catenanes using the tangle model for protein-bound DNA.