Locomotor projections from the pedunculopontine nucleus to the spinal cord.
Locomotor projections from the pedunculopontine nucleus to the spinal cord.
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DOI：
10.1097/00001756-199011000-00001
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发表时间：
1990-11
期刊：
影响因子：
1.7
通讯作者：
Robert D. Skinner;N. Kinjo;V. Henderson;E. Garcia-Rill
中科院分区：
文献类型：
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作者：
Robert D. Skinner;N. Kinjo;V. Henderson;E. Garcia-Rill
在脊髓扩大区注射逆行示踪剂后，电刺激去脑大鼠的中脑运动区(MLR)以诱发运动。MLR部位与胆碱能桥脑脚核(PPN)神经元重合，NADPH黄递酶组织化学选择性标记PPN神经元。逆行标记的PPN神经元散在分布于胆碱能PPN神经元之间。缺少逆行标记的NADPH黄递酶阳性的PPN神经元，表明脊髓增大投射是非胆碱能的。
Following injections of retrograde tracers into the spinal cord enlargements, the mesencephalic locomotor region (MLR) was electrically stimulated to induce locomotion in decerebrate rats. MLR sites coincided with cholinergic pedunculopontine nucleus (PPN) neurons, which were selectively labelled using NADPH diaphorase histochemistry. Retrogradely labelled (spinal-projecting) PPN neurons were scattered among cholinergic PPN neurons. The absence of retrogradely labelled, NADPH diaphorase positive PPN neurons indicates that spinal enlargement projections are non-cholinergic.