Left ventricular end-diastolic volume from ejection fraction and stroke volume in pigs during IVC occlusion.
Left ventricular end-diastolic volume from ejection fraction and stroke volume in pigs during IVC occlusion.
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IVC 闭塞期间猪的射血分数和每搏输出量的左心室舒张末期容积。
DOI：
10.1006/jsre.2002.6432
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
Spotnitz,HenryM
中科院分区：
文献类型：
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作者：
Gallup,CecilyJ;Cabreriza,SantosE;Hart,JosephP;Walsh,Rowan;Weinberg,Alan;Spotnitz,HenryM
背景实时测量左室舒张末期容积（LVEDV），结合左室舒张末期压（LVEDP），可以连续测量术中舒张功能。在追求这一目标，我们检查每搏输出量除以射血分数计算LVEDVsv/ef.MethodsFive麻醉猪进行正中胸骨切开术和心包切开术。升主动脉上的渡越时间超声流量探头提供心输出量。微压计提供LV舒张末期压。从左心室短轴横截面测量舒张末期和收缩末期面积以获得射血分数。计算IVC阻塞期间的LVEDVsv/ef。使用三平面超声心动图模型测定稳态LVEDVecho。LVEDVecho was used to validate steady state LVEDA in each experiments. ResultsLinear and pressure-volume relationship analysis相关系数为0.46 - 0.99。两种方法测得的左室舒张末容积的顺应性曲线的总体可靠性系数为0.84。结论LVEDVsv/eft法可用于实时测定左室顺应性。
BackgroundReal-time measurement of left ventricular end-diastolic volume (LVEDV), combined with left ventricular end-diastolic pressure (LVEDP), would allow continuous measurement of intraoperative diastolic function. In pursuit of this goal, we examined stroke volume divided by ejection fraction for calculation of LVEDVsv/ef.MethodsFive anesthetized pigs underwent median sternotomy and pericardiotomy. A transit-time ultrasonic flow probe on the ascending aorta provided cardiac output. A micromanometer provided LV end-diastolic pressure. End-diastolic and end-systolic areas were measured from LV short-axis cross sections to obtain ejection fraction. LVEDVsv/efwas calculated during IVC occlusion. Steady-state LVEDVechowas determined using a three-plane echocardiography model. LVEDVechowas used to validate steady-state LVEDA in each experiment.ResultsCorrelation coefficients for linear and pressure–volume relation analyses ranged from 0.46 to 0.99. The two methods for measuring LVEDV generated compliance curves with an overall reliability coefficient of 0.84.ConclusionsThe LVEDVsv/efmethod may facilitate real-time determination of LV compliance.