CRITICAL PERIODS IN CHILDHOOD FOR THE DEVELOPMENT OF OBESITY
CRITICAL PERIODS IN CHILDHOOD FOR THE DEVELOPMENT OF OBESITY
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DOI：
10.1093/ajcn/59.5.955
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发表时间：
1994-05-01
影响因子：
7.1
通讯作者：
DIETZ, WH
中科院分区：
文献类型：
--
作者：
DIETZ, WH
许多行为和发育过程的关键时期已经得到了很好的认可。然而，正如其他人指出的那样，营养性疾病的这种时期尚未得到广泛报道。许多观察表明，肥胖及其并发症的发展存在两个或三个关键时期。这些包括妊娠期和婴儿早期，发生在5至7岁之间的肥胖反弹期，以及青春期。在这些时期开始的肥胖似乎会增加持续性肥胖及其并发症的风险。这些年龄段肥胖风险增加的机制尚不清楚。尽管如此，关键时期的存在应有助于将预防工作的重点放在这些发展阶段。
Critical periods of development have been well recognized for many behavioral and developmental processes. However, as others have pointed out, such periods have not been widely reported for nutritional diseases. Many observations suggest that two and possibly three critical periods exist for the development of obesity and its complications. These include gestation and early infancy, the period of adiposity rebound that occurs between 5 and 7 y of age, and adolescence. Obesity that begins at these periods appears to increase the risk of persistent obesity and its complications. The mechanisms that account for the increased risk associated with obesity at these ages remain unclear. Nonetheless, the existence of critical periods should serve to focus preventive efforts on these developmental stages.