Age- and BMI-related variations of fat distribution in sacral and lumbar bone marrow and their association with local muscle fat content
Age- and BMI-related variations of fat distribution in sacral and lumbar bone marrow and their association with local muscle fat content
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DOI：
10.1038/s41598-020-66649-8
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发表时间：
2020-06-16
影响因子：
4.6
通讯作者：
Junker, Daniela
中科院分区：
文献类型：
--
作者：
Burian, Egon;Syvaeri, Jan;Junker, Daniela
该分析研究了骶骨和腰椎骨髓中脂肪分布的年龄和BMI相关变化及其与局部肌肉脂肪含量的相关性，以便使用质子密度脂肪分数（PDFF）测量来检测健康成人的脂肪分布模式和变化。在103名健康志愿者的骶骨和下腰椎区域，使用六回波3D扰相梯度回波序列进行基于化学位移编码的水脂分离。测定骶骨、第5腰椎椎体、臀肌和椎旁肌的PDFF值。与年龄相关显著（p
This analysis investigated the age- and BMI-related variations of fat distribution in sacral and lumbar bone marrow and their association with local muscle fat content in order to detect fat distribution patterns and variations in healthy adults using proton density fat fraction (PDFF) measurements. A six-echo 3D spoiled gradient-echo sequence was used for chemical shift encoding-based water-fat separation at the sacral and lower lumbar region in 103 healthy volunteers. PDFF values of the sacrum, 5(th) lumbar vertebral body, the gluteal and paraspinal muscles were determined. Correlation with age was significant (p