Layer analysis of axial spatial distribution of surface plasmon resonance sensing.
Layer analysis of axial spatial distribution of surface plasmon resonance sensing.
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DOI：
10.1016/j.aca.2020.09.044
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发表时间：
2020-11
影响因子：
6.2
通讯作者：
Yi Sun;H. Cai;Xiao-ping Wang;Shu-yue Zhan
中科院分区：
文献类型：
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作者：
Yi Sun;H. Cai;Xiao-ping Wang;Shu-yue Zhan
多吸附层、生物膜和细胞的空间分布检测和表征是研究生物分子性质和机制的重要技术。利用表面等离子体共振（SPR）技术，研究了倏逝波与复杂介质相互作用的空间特征、穿透机制和探测深度。此外，还分析了与轴向空间分布相关的参数。研究发现，轴向层状模型的空间折射率分布与不同波长的共振角、角谱一阶导数极值点和有效折射率三个特征参数具有独特的相关性。提出了一种新的基于波长扫描角度询问（WSAI）的层析方法，用于轴向空间介质的折射率测量。该方法扩展了SPR传感器的检测能力，为瞬变场中相互作用事件的分析提供了更精确的方法。
The spatial distribution detection and characterization of multi-adsorption layers, biomembranes, and cells are important techniques to study biomolecular properties and mechanisms. Using the surface plasmon resonance (SPR) technology, we investigated the spatial characteristics, penetration mechanism, and detection depth of the interaction between evanescent waves and a complex medium. In addition, parameters correlated with the axial spatial distribution were analyzed. We found that the spatial refractive-index distribution of an axial layered model has a unique correlation with the following three characteristic parameters: resonance angle at different wavelengths, first-derivative extreme-point of the angular spectrum, and effective refractive index. A new layer-analysis, based on wavelength-scanning angle interrogation (WSAI), was introduced to enable refractive-index measurements in an axial spatial medium. This new method extends the detection capabilities of SPR sensors and provides a more accurate analysis method for interaction events within an evanescent field.