Antiphospholipid antibodies in children

Antiphospholipid antibodies in children
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儿童抗磷脂抗体

DOI:
10.1111/j.1651-2227.1996.tb14098.x
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发表时间:
1996
期刊:
Acta Pædiatrica
影响因子:
--
通讯作者:
J. Mäenpää
J. Mäenpää
中科院分区:
--
文献类型:
--
作者:
Sirkka Kontiainen;A. Miettinen;I. Seppälä;M. Verkasalo;J. Mäenpää

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使用检测IgG抗心磷脂抗体(GPL)的酶免疫测定法检测儿童(n= 173)血清中的抗磷脂抗体(aPL)。还测试了来自成人(n= 100)的血清。GPL在儿童中的检出频率和水平高于成人。82%的儿童和27%的成人aPL检测呈阳性(≥ 10 GPL Uml-1)(p <0.001)。在约5%的儿童中检测到45 GPLUml-1或更高的值,在约5%的成人中检测到25 GPLUml-1或更高的值。应相应调整正常值。
Sera from children (n= 173) were tested for antiphospholipid antibodies (aPL) using an enzyme immunoassay detecting IgG anti‐cardiolipin antibodies (GPL). Sera from adults (n= 100) were also tested. GPL were detected more frequently and at higher levels in children than in adults. Eighty‐two percent of the children and 27% of the adults tested positive (≥ 10 GPL Uml‐1) for aPL (p <0.001). Values of 45 GPLUml‐1 or higher were detected in about 5% of the children, and 25 GPLUml‐1 or higher in about 5% of the adults. Normal values should be adjusted accordingly.
DOI: --
发表时间: 1995
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Roubey,RA;Eisenberg,RA;Harper,MF;Winfield,JB
通讯作者: Winfield,JB