Rapid transition from drinking to alcohol dependence among adolescent and young-adult newly incident drinkers in the United States, 2002-2013
Rapid transition from drinking to alcohol dependence among adolescent and young-adult newly incident drinkers in the United States, 2002-2013
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DOI：
10.1016/j.drugalcdep.2016.08.015
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发表时间：
2016-11-01
影响因子：
4.2
通讯作者：
Anthony, James C.
中科院分区：
文献类型：
--
作者：
Cheng, Hui G.;Chandra, Madhur;Anthony, James C.
背景资料：为了研究男性-女性和年龄差异的估计快速过渡到酒精依赖的年轻的新事件饮酒者在美国（US）。方法：研究人群包括12-25岁的非制度化的美国平民居民，抽样为美国全国调查药物使用和健康2002-2013年，通过保密的计算机辅助自我访谈评估。新发生的饮酒者是那些在评估前不久第一次喝满酒的人（n=32,562名12至25奥尔兹的人）。酒精依赖（AD）标准来自DSMIV。结果：对于12-25岁的女性，从第一次充分饮酒到酒精依赖的快速转变的风险峰值出现在青春期，随后估计值下降（荟萃分析总结= 3%，12-17岁，95%CI = 2%，3%）。在男性中，相应的估计值在2%左右波动，各年龄层之间没有明显差异。在12至17岁的新事件饮酒者中，有一个女性过量的快速过渡到酒精依赖;男性过量的年轻成年人新事件饮酒者中观察到。评估队列明智的，使用流行病学mutoscope的观点，个别队列表现出一致的模式，与年龄在第一次喝酒constant.Conclusions：研究多个重复样本的年轻新事件饮酒者，我们发现了一个明确的女性过剩的风险，从第一次充分饮酒到酒精依赖的青少年之间的快速过渡，年龄模式不同的男性和女性。(C)2016爱思唯尔爱尔兰有限公司版权所有。
Background: To study male-female and age differences in estimates of rapid transition from first full drink to alcohol dependence among youthful newly incident drinkers in the United States (US).Method: The study population included 12-to-25-year-old non-institutionalized US civilian residents, sampled for US National Surveys on Drug Use and Health 2002-2013, with assessments via confidential computer assisted self-interviews. Newly incident drinkers are those who had their first full drink soon before the assessment (n=32,562 12-to-25- year- olds). Alcohol dependence (AD) criteria are from DSMIV.Results: For 12-to-25-year-old females, the peak risk for making a rapid transition from first full drink to alcohol dependence is seen during adolescence, followed by declining estimates (meta-analysis summary = 3% at 12-17 years of age, 95% CI = 2%, 3%). Among males, corresponding estimates fluctuate around 2%, with no appreciable differences across age strata. Among 12-to-17-year-old newly incident drinkers, there is a female excess in the rapid transition to alcohol dependence; a male excess is observed among young adult newly incident drinkers. Evaluated cohort-wise, using an epidemiological mutoscope view, individual cohorts show a congruent pattern, with age at first drink held constant.Conclusions: Studying multiple replication samples of young newly incident drinkers, we discovered a clear female excess in the risk of a rapid transition from first full drink to alcohol dependence among adolescents, with age patterns differing across males and females. (C) 2016 Elsevier Ireland Ltd. All rights reserved.