Stretching and relaxation of vesicles.
Stretching and relaxation of vesicles.
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囊泡的拉伸和松弛。
DOI：
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
W. van de Water
中科院分区：
文献类型：
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作者：
Hernan Zhou;Beatriz Burrola Gabilondo;W. Losert;W. van de Water
我们使用光镊研究了球形巨型单层囊泡的形状弛豫，这些囊泡已远离平衡变形为椭球体。松弛回到球体是由囊泡的弹性常数及其过剩面积、从热平衡中的形状波动以及低雷诺数流体流动中为每个拉伸囊泡获得的参数决定的。弛豫时间可以与包含膜刚性和流体流动的联合效应的简单公式进行比较。拉伸囊泡的时间常数比其热波动的时间常数慢，这与最近的理论一致；然而，它比预期快一个数量级。
We study the shape relaxation of spherical giant unilamellar vesicles which have been deformed far from equilibrium into ellipsoids using optical tweezers. The relaxation back to a sphere is determined by elastic constants of the vesicles, and their excess area, parameters that are obtained for each stretched vesicle from shape fluctuations in thermal equilibrium, as well as low Reynolds number fluid flow. The relaxation time could be compared favorably to a simple formula which encompasses the joint effect of membrane rigidity and fluid flow. The time constant of the stretched vesicle is slower than that of its thermal fluctuations, which agrees with a recent theory; however, it is one order of magnitude faster than predicted.