Cerebral glucose metabolic rates in nondepressed patients with obsessive-compulsive disorder.
Cerebral glucose metabolic rates in nondepressed patients with obsessive-compulsive disorder.
复制标题
患有强迫症的非抑郁患者的脑葡萄糖代谢率。
DOI：
10.1176/ajp.145.12.1560
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Fairbanks,L
中科院分区：
文献类型：
--
作者：
BaxterJr,LR;Schwartz,JM;Mazziotta,JC;Phelps,ME;Pahl,JJ;Guze,BH;Fairbanks,L
作者将 10 名患有强迫症的非抑郁症患者与 10 名同性别、相似年龄的正常对照受试者进行了比较，以使用正电子发射断层扫描获得脑葡萄糖代谢率。强迫症患者的整个大脑半球、尾状核头、眶回以及眶回相对同侧半球的代谢率（眶半球比率）显着升高。这些结果与作者之前针对另一组强迫症患者和正常对照受试者报告的结果相似。
The authors compared 10 nondepressed patients with obsessive-compulsive disorder with 10 normal control subjects of the same sex and similar age for cerebral glucose metabolic rates obtained using positron emission tomography. Obsessive-compulsive patients showed significantly elevated metabolic rates in the whole cerebral hemispheres, heads of the caudate nuclei, orbital gyri, and the orbital gyri relative to the ipsilateral hemisphere (the orbital-hemisphere ratio). These results are similar to those the authors reported previously for another group of obsessive-compulsive patients and normal control subjects.