Plasma vasopressin and blood pressure. Studies in normal subjects and in benign essential hypertension at rest and after postural challenge.
Plasma vasopressin and blood pressure. Studies in normal subjects and in benign essential hypertension at rest and after postural challenge.
复制标题
血浆加压素和血压。
作者：
R. Davies;M. Forsling;G. Bulger;T. Phillips
比较了正常血压、轻度高血压和重度高血压患者三组的血浆加压素水平，这三组患者在基础状态下和仰卧位85度后，已知刺激人体释放加压素。在倾斜后，所有受试者的加压素水平都增加了两到五倍；然而，倾斜后45到60分钟达到的基础水平和最大水平在三组中都没有不同。这些数据并不支持加压素在人类非加速性高血压的病因或持续性中的假设作用。
Plasma vasopressin levels were compared in three groups comprising normotensive, mildly hypertensive, and more severely hypertensive patients, both under basal conditions and following an 85 degrees head-up tilt, a stimulus known to provoke vasopressin release in man. Vasopressin levels increased two- to fivefold in all subjects after tilt; however, neither the basal levels nor the maximal levels attained at 45 to 60 minutes after tilt differed in the three groups. These data do not support the postulated role for vasopressin in the causation or perpetuation of non-accelerated essential hypertension in man.